Benzamide, 4-(4-piperidinylamino)-2-propoxy-

Base Information

Chemical Name:Benzamide, 4-(4-piperidinylamino)-2-propoxy-
CAS No.:609782-78-7
Molecular Formula:C15H23N3O2
Molecular Weight:277.367
Hs Code.:

Synonyms:

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Chemical Property of Benzamide, 4-(4-piperidinylamino)-2-propoxy-

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Technology Process of Benzamide, 4-(4-piperidinylamino)-2-propoxy-

There total 5 articles about Benzamide, 4-(4-piperidinylamino)-2-propoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 609782-74-3
4-[(1-benzylpiperidin-4-yl)amino]-2-propoxybenzamide

: 609782-78-7
4-(piperidin-4-ylamino)-2-propoxybenzamide

Guidance literature:: With ammonium formate; palladium 10% on activated carbon; In ethanol; for 4h; Heating / reflux;

Reference yield:

: 609781-50-2
methyl 2-methoxy-4-[(1-benzylpiperidin-4-yl)amino]benzoate

: 609782-78-7
4-(piperidin-4-ylamino)-2-propoxybenzamide

Guidance literature:: Multi-step reaction with 5 steps

1: sodium hydroxide; water / tetrahydrofuran; methanol / 20 °C

2: ammonium chloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / DMF (N,N-dimethyl-formamide) / 20 °C

3: boron tribromide / dichloromethane / 20 °C

4: potassium carbonate / DMF (N,N-dimethyl-formamide) / 5 h / 70 °C

5: ammonium formate / palladium 10% on activated carbon / ethanol / 4 h / Heating / reflux

With sodium hydroxide; water; ammonium formate; boron tribromide; potassium carbonate; ammonium chloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; palladium 10% on activated carbon; In tetrahydrofuran; methanol; DMF (N,N-dimethyl-formamide); ethanol; dichloromethane;

Reference yield:

: 609782-62-9
4-[(1-benzylpiperidin-4-yl)amino]-2-hydroxybenzamide

: 609782-78-7
4-(piperidin-4-ylamino)-2-propoxybenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / DMF (N,N-dimethyl-formamide) / 5 h / 70 °C

2: ammonium formate / palladium 10% on activated carbon / ethanol / 4 h / Heating / reflux

With ammonium formate; potassium carbonate; palladium 10% on activated carbon; In DMF (N,N-dimethyl-formamide); ethanol;