2-Propanone, 1-chloro-1-(2-chlorophenyl)-

Base Information

• Chemical Name: 2-Propanone, 1-chloro-1-(2-chlorophenyl)-
• CAS No.: 37610-57-4
• Molecular Formula: C₉H₈Cl₂O
• Molecular Weight: 203.068
• NSC Number: 327170
• Mol file: 37610-57-4.mol

Synonyms:37610-57-4;NSC 327170;2-Propanone, 1-chloro-1-(2-chlorophenyl)-;NSC327170;AKOS022397490;NSC-327170

Chemical Property of 2-Propanone, 1-chloro-1-(2-chlorophenyl)-

Chemical Property:

• Vapor Pressure: 0.0127mmHg at 25°C
• Boiling Point: 259.8°C at 760 mmHg
• Flash Point: 107.2°C
• Density: 1.269g/cm³
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 201.9952203
• Heavy Atom Count: 12
• Complexity: 170

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)C(C1=CC=CC=C1Cl)Cl

Technology Process of 2-Propanone, 1-chloro-1-(2-chlorophenyl)-

There total 3 articles about 2-Propanone, 1-chloro-1-(2-chlorophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloropropiophenone (6323-18-8) → 1-(o-Chlorphenyl)-1-chlorpropan-2-on (37610-57-4)

Guidance literature:

Multi-step reaction with 3 steps

1: Cl₂, NaOAc / acetic acid

2: NaBH₄ / methanol

3: H₂SO₄

With sodium tetrahydroborate; sulfuric acid; sodium acetate; chlorine; In methanol; acetic acid;

DOI:10.1021/jo00944a056

Reference yield:

1-(o-Chlorophenyl)-2,2-dichloro-1-propanone (35996-45-3) → 1-(o-Chlorphenyl)-1-chlorpropan-2-on (37610-57-4)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄ / methanol

2: H₂SO₄

With sodium tetrahydroborate; sulfuric acid; In methanol;

DOI:10.1021/jo00944a056

Reference yield:

1-(o-Chlorphenyl)-2,2-dichlorpropanol (35996-56-6) → 1-(o-Chlorphenyl)-1-chlorpropan-2-on (37610-57-4)

Guidance literature:

With sulfuric acid;

DOI:10.1021/jo00944a056 DOI:10.1016/S0040-4039(01)83034-3

upstream raw materials:

1-(o-Chlorphenyl)-2,2-dichlorpropanol

2-chloropropiophenone

1-(o-Chlorophenyl)-2,2-dichloro-1-propanone