Oxazolo(5,4-b)pyridin-2(1H)-one, 1-(4-bromobutyl)-

Base Information

Chemical Name:Oxazolo(5,4-b)pyridin-2(1H)-one, 1-(4-bromobutyl)-
CAS No.:142714-74-7
Molecular Formula:C10H11 Br N2 O2
Molecular Weight:271.114
Hs Code.:
DSSTox Substance ID:DTXSID60162138
Wikidata:Q83030699

Synonyms:1-(4-Bromobutyl)oxazolo(5,4-b)pyridin-2(1H)-one;Oxazolo(5,4-b)pyridin-2(1H)-one, 1-(4-bromobutyl)-;142714-74-7;SCHEMBL9263753;DTXSID60162138;LS-100889

Suppliers and Price of Oxazolo(5,4-b)pyridin-2(1H)-one, 1-(4-bromobutyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Oxazolo(5,4-b)pyridin-2(1H)-one, 1-(4-bromobutyl)-

Chemical Property:

Vapor Pressure:3.75E-06mmHg at 25°C
Boiling Point:385.6°Cat760mmHg
Flash Point:187°C
Density:1.557g/cm³
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:270.00039
Heavy Atom Count:15
Complexity:238

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(N=C1)OC(=O)N2CCCCBr

Technology Process of Oxazolo(5,4-b)pyridin-2(1H)-one, 1-(4-bromobutyl)-

There total 3 articles about Oxazolo(5,4-b)pyridin-2(1H)-one, 1-(4-bromobutyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 142714-74-7
1-(4-bromobutyl)oxazolo<5,4-b>pyridin-2(1H)-one

Guidance literature:

Reference yield:

: 33630-99-8
3-amino-2-pyridone

: 142714-74-7
1-(4-bromobutyl)oxazolo<5,4-b>pyridin-2(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / NEt₃ / CH₂Cl₂; tetrahydrofuran / 6 h / -78 °C

2: 1.) NaH / 1.) DMF, 40-50 deg C, 40 min, 2.) DMF, 110 deg C, 1 h

With sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(00)61315-1

Reference yield:

: 110-52-1
1,4-dibromo-butane

: 118767-92-3
oxazolo[5,4-b]pyridin-2(3H)-one

: 142714-74-7
1-(4-bromobutyl)oxazolo<5,4-b>pyridin-2(1H)-one

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) DMF, 40-50 deg C, 40 min, 2.) DMF, 110 deg C, 1 h;
DOI:10.1016/S0040-4039(00)61315-1