7-Chloro-5,6-dimethylpyrazolo[1,5-A]pyrimidine

Base Information

Chemical Name:7-Chloro-5,6-dimethylpyrazolo[1,5-A]pyrimidine
CAS No.:61098-39-3
Molecular Formula:C8H8ClN3
Molecular Weight:181.62200
Hs Code.:2933990090
European Community (EC) Number:877-738-2
DSSTox Substance ID:DTXSID30494478
Wikidata:Q82341863
Mol file:61098-39-3.mol

Synonyms:7-CHLORO-5,6-DIMETHYLPYRAZOLO[1,5-A]PYRIMIDINE;61098-39-3;SCHEMBL7830112;DTXSID30494478;MFCD11215524;AKOS013133813;AB63878;AT27589;CS-0225929;EN300-1252640;Z1157836267

Suppliers and Price of 7-Chloro-5,6-dimethylpyrazolo[1,5-A]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemBridge Corporation
7-chloro-5,6-dimethylpyrazolo[1,5-a]pyrimidine 95%
5 g
$ 1030.00

Total 5 raw suppliers

Chemical Property of 7-Chloro-5,6-dimethylpyrazolo[1,5-A]pyrimidine

Chemical Property:

PSA：30.19000
LogP:1.99950
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:181.0406750
Heavy Atom Count:12
Complexity:176

Purity/Quality:

98%min ^*data from raw suppliers

7-chloro-5,6-dimethylpyrazolo[1,5-a]pyrimidine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N2C(=CC=N2)N=C1C)Cl

Technology Process of 7-Chloro-5,6-dimethylpyrazolo[1,5-A]pyrimidine

There total 4 articles about 7-Chloro-5,6-dimethylpyrazolo[1,5-A]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 61098-36-0
5,6-dimethyl-7-hydroxypyrazolo[1,5-a]pyrimidine

: 61098-39-3
5,6-dimethyl-7-chloropyrazolo[1,5-a]pyrimidine

Guidance literature:: With trichlorophosphate; In acetonitrile; for 1h; Reflux; Inert atmosphere;
DOI:10.1021/acsmedchemlett.1c00216

Reference yield: 50.0%

: 61098-39-3
5,6-dimethyl-7-chloropyrazolo[1,5-a]pyrimidine

Guidance literature:: With trichlorophosphate; In N,N-dimethyl-aniline; at 35 ℃; for 36h;

Reference yield:

: 17094-21-2
2-methyl-acetoacetic acid methyl ester

: 61098-39-3
5,6-dimethyl-7-chloropyrazolo[1,5-a]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 3 h / 110 °C / Inert atmosphere

2: trichlorophosphate / acetonitrile / 1 h / Reflux; Inert atmosphere

With trichlorophosphate; In acetic acid; acetonitrile;
DOI:10.1021/acsmedchemlett.1c00216