URIDINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT

Base Information

• Chemical Name: URIDINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
• CAS No.: 56632-58-7
• Molecular Formula: C9H11 N2 O8 P . Na
• Molecular Weight: 328.151
• Mol file: 56632-58-7.mol

Synonyms:4H-Furo[3,2-d]-1,3,2-dioxaphosphorin,uridine deriv.; Cyclic 3',5'-uridine monophosphate monosodium salt; Sodiumuridine-3',5'-phosphate

Chemical Property of URIDINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT

Chemical Property:

• PSA: 152.72000
• LogP: -1.25110
• Storage Temp.: −20°C

Purity/Quality:

99% ^*data from raw suppliers

Cumpsodiumsalt 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Uridine-3’,5’-cyclic Monophosphate is a Uridine (U829910) derivative showed antitumor and antiviral activity.

Technology Process of URIDINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT

There total 2 articles about URIDINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.2%

D-ImpU → C27H32N6O25P3(3-)*3Na(1+) + C18H20N4O16P2(2-)*2Na(1+) + C18H22N4O17P2(2-)*Na(1+) + uridine 3',5'-cyclic monophosphate sodium salt (56632-58-7)

Guidance literature:

With lead(II) nitrate; In water; at 20 ℃; for 120h; imidazole buffer, pH 6.5;

DOI:10.1248/cpb.29.2237

Reference yield:

uridine-5'-monophosphate sodium salt (3106-18-1,3387-36-8,7545-48-4,19325-99-6,26760-90-7,75873-93-7) → P1,P2-diuridine-5',5'-diphosphate disodium salt + uridine 3',5'-cyclic monophosphate sodium salt (56632-58-7)

Guidance literature:

With dicyclohexyl-carbodiimide;

DOI:10.1248/cpb.29.2237

Reference yield: 65.0%

uridine 3',5'-cyclic monophosphate sodium salt (56632-58-7) → 5-iodouridine 3',5'-cyclic monophosphate ammonium salt (99641-48-2)

Guidance literature:

With N-iodo-succinimide; acetic acid; at 118 ℃; for 0.5h;

DOI:10.1021/jm00154a011

upstream raw materials:

uridine-5'-monophosphate sodium salt

Downstream raw materials:

5-iodouridine 3',5'-cyclic monophosphate ammonium salt

5-chlorouridine 3',5'-cyclic monophosphate ammonium salt

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