Phenol, 4-[(2-aminoethyl)thio]-2,6-bis(1,1-dimethylethyl)-

Base Information

Chemical Name:Phenol, 4-[(2-aminoethyl)thio]-2,6-bis(1,1-dimethylethyl)-
CAS No.:61151-55-1
Molecular Formula:C16H27NOS
Molecular Weight:281.462
Hs Code.:
DSSTox Substance ID:DTXSID60443515
Nikkaji Number:J498.448J

Synonyms:61151-55-1;Phenol, 4-[(2-aminoethyl)thio]-2,6-bis(1,1-dimethylethyl)-;DTXSID60443515;4-[(2-Aminoethyl)thio]-2,6-bis(1,1-dimethylethyl)phenol

Suppliers and Price of Phenol, 4-[(2-aminoethyl)thio]-2,6-bis(1,1-dimethylethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Phenol, 4-[(2-aminoethyl)thio]-2,6-bis(1,1-dimethylethyl)-

Chemical Property:

XLogP3:4.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:281.18133566
Heavy Atom Count:19
Complexity:256

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SCCN

Technology Process of Phenol, 4-[(2-aminoethyl)thio]-2,6-bis(1,1-dimethylethyl)-

There total 4 articles about Phenol, 4-[(2-aminoethyl)thio]-2,6-bis(1,1-dimethylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 155722-06-8
(3,5-di-tert-butyl-4-hydroxyphenylthio)acetamide

: 61151-55-1
2-(3,5-di-tert-butyl-4-hydroxyphenylthio)ethylamine

Guidance literature:: With dimethylsulfide borane complex; In tetrahydrofuran; Heating;
DOI:10.1021/jm990945v

Reference yield:

: 1139-52-2
4-bromo-2,6-di-tert-butylphenol

: 61151-55-1
2-(3,5-di-tert-butyl-4-hydroxyphenylthio)ethylamine

Guidance literature:: Multi-step reaction with 4 steps

1.1: 97 percent / n-BuLi / tetrahydrofuran / -78 - 20 °C

2.1: t-BuLi; sulfur / tetrahydrofuran / -78 - -30 °C

2.2: tetrahydrofuran

3.1: 57 percent / Bu₄NF / methanol / Heating

4.1: 100 percent / BH₃*Me₂S / tetrahydrofuran / Heating

With n-butyllithium; dimethylsulfide borane complex; tetrabutyl ammonium fluoride; tert.-butyl lithium; sulfur; In tetrahydrofuran; methanol; 1.1: Silylation / 2.1: Sulfurization / 2.2: Alkylation / 3.1: Desilylation / 4.1: Reduction;
DOI:10.1021/jm990945v

Reference yield:

: 27329-74-4
(4-Bromo-2,6-di-tert-butylphenoxy)trimethylsilane

: 61151-55-1
2-(3,5-di-tert-butyl-4-hydroxyphenylthio)ethylamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: t-BuLi; sulfur / tetrahydrofuran / -78 - -30 °C

1.2: tetrahydrofuran

2.1: 57 percent / Bu₄NF / methanol / Heating

3.1: 100 percent / BH₃*Me₂S / tetrahydrofuran / Heating

With dimethylsulfide borane complex; tetrabutyl ammonium fluoride; tert.-butyl lithium; sulfur; In tetrahydrofuran; methanol; 1.1: Sulfurization / 1.2: Alkylation / 2.1: Desilylation / 3.1: Reduction;
DOI:10.1021/jm990945v