Benzamide, N-[2-(2,4,5-trimethoxyphenyl)ethyl]-

Base Information

• Chemical Name: Benzamide, N-[2-(2,4,5-trimethoxyphenyl)ethyl]-
• CAS No.: 61177-93-3
• Molecular Formula: C₁₈H₂₁NO₄
• Molecular Weight: 315.369
• Mol file: 61177-93-3.mol

Synonyms:

Chemical Property of Benzamide, N-[2-(2,4,5-trimethoxyphenyl)ethyl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzamide, N-[2-(2,4,5-trimethoxyphenyl)ethyl]-

There total 6 articles about Benzamide, N-[2-(2,4,5-trimethoxyphenyl)ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-[2-(4-methoxy-3,6-dioxo-cyclohexa-1,4-dienyl)-ethyl]-benzamide → N-(2,4,5-trimethoxy-phenethyl)-benzamide (61177-93-3)

Guidance literature:

Multi-step reaction with 2 steps

1: Na₂S₂O₄; aqueous methanol

2: aqueous NaOH

With methanol; sodium hydroxide; sodium dithionite;

DOI:10.1021/ja01532a028

Reference yield:

N-(3,4-dihydroxyphenethyl)benzamide (54210-14-9) → N-(2,4,5-trimethoxy-phenethyl)-benzamide (61177-93-3)

Guidance literature:

Multi-step reaction with 3 steps

1: Na₂SO₄; Ag₂O; methanol / Umsetzen mit Aether-BF₃

2: Na₂S₂O₄; aqueous methanol

3: aqueous NaOH

With methanol; sodium hydroxide; sodium dithionite; sodium sulfate; silver(l) oxide;

DOI:10.1021/ja01532a028

Reference yield:

dopamine hydrochloride (62-31-7) → N-(2,4,5-trimethoxy-phenethyl)-benzamide (61177-93-3)

Guidance literature:

Multi-step reaction with 4 steps

1: diethyl ether / unter Zusatz von wss.NaHCO₃

2: Na₂SO₄; Ag₂O; methanol / Umsetzen mit Aether-BF₃

3: Na₂S₂O₄; aqueous methanol

4: aqueous NaOH

With methanol; sodium hydroxide; sodium dithionite; diethyl ether; sodium sulfate; silver(l) oxide;

DOI:10.1021/ja01532a028

upstream raw materials:

dimethyl sulfate

N-(3,4-dihydroxyphenethyl)benzamide

dopamine hydrochloride

benzoyl chloride