1-(4-Fluorophenyl)pyrazolidin-3-one

Base Information

Chemical Name:1-(4-Fluorophenyl)pyrazolidin-3-one
CAS No.:6119-11-5
Molecular Formula:C9H9FN2O
Molecular Weight:180.17900
Hs Code.:
DSSTox Substance ID:DTXSID80607718
Wikidata:Q82506792
Mol file:6119-11-5.mol

Synonyms:6119-11-5;1-(4-Fluorophenyl)pyrazolidin-3-one;1-(4-FLUOROPHENYL)-3-HYDROXY-4,5-DIHYDRO-1H-PYRAZOLE;starbld0004492;SCHEMBL11140093;DTXSID80607718;AKOS006291471;1-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-ol

Suppliers and Price of 1-(4-Fluorophenyl)pyrazolidin-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(4-Fluorophenyl)-3-pyrazolidinone
1mg
$ 45.00

American Custom Chemicals Corporation
1-(4-FLUOROPHENYL)-3-HYDROXY-2-PYRAZOLINE 95.00%
5MG
$ 499.65

Total 6 raw suppliers

Chemical Property of 1-(4-Fluorophenyl)pyrazolidin-3-one

Chemical Property:

PSA：35.83000
LogP:1.40790
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:180.06989108
Heavy Atom Count:13
Complexity:202

Purity/Quality:

98% ^*data from raw suppliers

1-(4-Fluorophenyl)-3-pyrazolidinone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(NC1=O)C2=CC=C(C=C2)F

Technology Process of 1-(4-Fluorophenyl)pyrazolidin-3-one

There total 2 articles about 1-(4-Fluorophenyl)pyrazolidin-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 823-85-8
4-fluorophenyhydrazine hydrochloride

: 292638-85-8,9003-21-8,96-33-3
acrylic acid methyl ester

: 6119-11-5
1-(4-fluorophenyl)pyrazolidin-3-one

Guidance literature:: With sodium methylate; In methanol; toluene; at 30 ℃; Reflux;
DOI:10.3184/174751918X15161933697808

Reference yield: 70.0%

: 823-85-8
4-fluorophenyhydrazine hydrochloride

: 140-88-5,9003-32-1
ethyl acrylate

: 6119-11-5
1-(4-fluorophenyl)pyrazolidin-3-one

Guidance literature:: 4-fluorophenyhydrazine hydrochloride; With potassium tert-butylate; In methanol; toluene; at 20 ℃; for 0.5h; Inert atmosphere;

ethyl acrylate; In methanol; toluene; at 50 ℃; for 24h;
DOI:10.24820/ark.5550190.p010.407

Reference yield: 89.0%

: 6119-11-5
1-(4-fluorophenyl)pyrazolidin-3-one

: 4-bromo-1-(4-fluorophenyl)-1H-pyrazole-3-ol

Guidance literature:: With hydrogen bromide; dihydrogen peroxide; In chloroform; water; at 60 ℃; for 0.5h; Green chemistry;
DOI:10.1515/hc-2018-0046