1-Piperidineacetamide, N-(2-((4-chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)-

Base Information

Chemical Name:1-Piperidineacetamide, N-(2-((4-chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)-
CAS No.:59180-45-9
Molecular Formula:C23H25Cl2N3O3
Molecular Weight:462.3689
Hs Code.:
DSSTox Substance ID:DTXSID40207915
Wikidata:Q83081926
ChEMBL ID:CHEMBL91593

Synonyms:BRN 5170730;1-Piperidineacetamide, N-(2-((4-chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)-;N-(2-((4-Chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)-1-piperidineacetamide;59180-45-9;CHEMBL91593;C23H25Cl2N3O3;DTXSID40207915;C23-H25-Cl2-N3-O3;LS-113897

Suppliers and Price of 1-Piperidineacetamide, N-(2-((4-chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Piperidineacetamide, N-(2-((4-chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)-

Chemical Property:

Vapor Pressure:5.81E-19mmHg at 25°C
Boiling Point:691.3°Cat760mmHg
Flash Point:371.9°C
Density:1.3g/cm³
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:461.1272971
Heavy Atom Count:31
Complexity:642

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C1=C(C=C(C=C1)Cl)C(=O)C2=CC=CC=C2Cl)C(=O)CNC(=O)CN3CCCCC3

Technology Process of 1-Piperidineacetamide, N-(2-((4-chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)-

There total 3 articles about 1-Piperidineacetamide, N-(2-((4-chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 110-89-4
piperidine

: 59180-43-7
4-chloro-2-(o-chlorobenzoyl)-N-methyl-N^α-(iodoacetyl)glycinanilide

: 59180-45-9
N-({[4-Chloro-2-(2-chloro-benzoyl)-phenyl]-methyl-carbamoyl}-methyl)-2-piperidin-1-yl-acetamide

Guidance literature:: In methanol; ethanol; chloroform; for 3h; Ambient temperature;
DOI:10.1021/jm00133a006

Reference yield:

: 29176-39-4
4-chloro-2-(o-chlorobenzoyl)-N^α-(benzyloxycarbonyl)glycinanilide

: 59180-45-9
N-({[4-Chloro-2-(2-chloro-benzoyl)-phenyl]-methyl-carbamoyl}-methyl)-2-piperidin-1-yl-acetamide

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) NaH / 1.) DMF, oil, 2-5 deg C, 15 min, 2.) DMF, oil, 2-5 deg C, 2 h

2: 97 percent / 20percent HBr / acetic acid / 1 h / Ambient temperature

3: 89 percent / hexamethylphosphoric acid triamide / 5 h

4: 91.5 percent / KI / acetone / 1 h / Heating

5: 100 percent / ethanol; CHCl₃; methanol / 3 h / Ambient temperature

With hydrogen bromide; sodium hydride; potassium iodide; In methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol; chloroform; acetic acid; acetone;
DOI:10.1021/jm00133a006

Reference yield:

: 59180-42-6
4-chloro-2-(o-chlorobenzoyl)-N-methyl-N^α-(chloroacetyl)glycinanilide

: 59180-45-9
N-({[4-Chloro-2-(2-chloro-benzoyl)-phenyl]-methyl-carbamoyl}-methyl)-2-piperidin-1-yl-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 91.5 percent / KI / acetone / 1 h / Heating

2: 100 percent / ethanol; CHCl₃; methanol / 3 h / Ambient temperature

With potassium iodide; In methanol; ethanol; chloroform; acetone;
DOI:10.1021/jm00133a006