N-phenylnaphthalene-1-sulfonamide

Base Information

• Chemical Name: N-phenylnaphthalene-1-sulfonamide
• CAS No.: 61209-69-6
• Molecular Formula: C16H13NO2S
• Molecular Weight: 283.351
• DSSTox Substance ID: DTXSID00396819
• Nikkaji Number: J500.972C
• Wikidata: Q82197733
• Mol file: 61209-69-6.mol

Synonyms:N-phenylnaphthalene-1-sulfonamide;61209-69-6;1-Naphthalenesulfonamide, N-phenyl-;1-Naphthalenesulfonanilide;SCHEMBL812673;DTXSID00396819

Chemical Property of N-phenylnaphthalene-1-sulfonamide

Chemical Property:

• PSA: 54.55000
• LogP: 4.79440
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 283.06669983
• Heavy Atom Count: 20
• Complexity: 409

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC3=CC=CC=C32

Technology Process of N-phenylnaphthalene-1-sulfonamide

There total 10 articles about N-phenylnaphthalene-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

naphthalene-1-sulfonyl azide (13407-53-9) + phenylboronic acid (98-80-6) → N-phenylnaphthalene-1-sulfonamide (61209-69-6)

Guidance literature:

With copper(l) chloride; In methanol; at 20 ℃; for 1h;

DOI:10.1021/ol403717

Reference yield: 84.0%

1-Naphthylboronic acid (13922-41-3) + nitrobenzene (98-95-3,26969-40-4) → N-phenylnaphthalene-1-sulfonamide (61209-69-6)

Guidance literature:

With potassium pyrosulfite; tetrabutyl-ammonium chloride; potassium carbonate; In acetonitrile; at 130 ℃; for 24h; Sealed tube;

DOI:10.1021/acs.orglett.0c00183

Reference yield: 75.0%

tri(naphthalen-1-yl)bismuth (33397-22-7) + nitrobenzene (98-95-3,26969-40-4) → N-phenylnaphthalene-1-sulfonamide (61209-69-6)

Guidance literature:

With sodium metabisulfite; copper(l) chloride; In melt; at 80 ℃; for 24h; chemoselective reaction; Green chemistry;

DOI:10.1039/c9gc01541h

upstream raw materials:

1-Naphthalenesulfonyl chloride

aniline

1-Naphthalenethiol

naphthalene-1-sulfonyl azide