Technology Process of Pyridine,
4-[3,4-dihydro-5-(4-methoxyphenyl)-2,2-dimethyl-2H-pyrrol-3-yl]-, (R)-
There total 8 articles about Pyridine,
4-[3,4-dihydro-5-(4-methoxyphenyl)-2,2-dimethyl-2H-pyrrol-3-yl]-, (R)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 50 percent / benzene / 8 h / Irradiation
2: (+)-camphorsulfonic acid / ethyl acetate; acetonitrile / Heating
With
(+)-10-camphorsulfonic acid;
In
ethyl acetate; acetonitrile; benzene;
DOI:10.1002/hlca.19800630310
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 83 percent / base
2: 80.1 percent / NaOEt solution / Heating
3: 78.8 percent / H2 / Raney-nickel / ethanol / 6 h / 70 °C
4: (+)-camphorsulfonic acid / ethyl acetate; acetonitrile / Heating
With
hydrogen; sodium ethanolate; (+)-10-camphorsulfonic acid;
nickel;
In
ethanol; ethyl acetate; acetonitrile;
DOI:10.1002/hlca.19800630310
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 80.1 percent / NaOEt solution / Heating
2: 78.8 percent / H2 / Raney-nickel / ethanol / 6 h / 70 °C
3: (+)-camphorsulfonic acid / ethyl acetate; acetonitrile / Heating
With
hydrogen; sodium ethanolate; (+)-10-camphorsulfonic acid;
nickel;
In
ethanol; ethyl acetate; acetonitrile;
DOI:10.1002/hlca.19800630310
