Cyclohexanol, 2-(2-methylphenyl)-, trans-

Base Information

Chemical Name:Cyclohexanol, 2-(2-methylphenyl)-, trans-
CAS No.:6125-71-9
Molecular Formula:C₁₃H₁₈O
Molecular Weight:190.285
Hs Code.:
DSSTox Substance ID:DTXSID60460469
Wikidata:Q82284522

Synonyms:Cyclohexanol, 2-(2-methylphenyl)-, trans-;6125-71-9;trans-2-o-tolylcyclohexanol;DTXSID60460469

Suppliers and Price of Cyclohexanol, 2-(2-methylphenyl)-, trans-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Cyclohexanol, 2-(2-methylphenyl)-, trans-

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:190.135765193
Heavy Atom Count:14
Complexity:178

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=CC=C1C2CCCCC2O
Isomeric SMILES:CC1=CC=CC=C1[C@@H]2CCCC[C@H]2O

Technology Process of Cyclohexanol, 2-(2-methylphenyl)-, trans-

There total 5 articles about Cyclohexanol, 2-(2-methylphenyl)-, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 95-46-5
2-methylphenyl bromide

: 286-20-4
cyclohexane-1,2-epoxide

: 523-25-1,6125-71-9,15315-32-9,18180-77-3,21481-86-7
(+/-)-trans-2-(2-methylphenyl)cyclohexan-1-ol

Guidance literature:: 2-methylphenyl bromide; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

cyclohexane-1,2-epoxide; With boron trifluoride diethyl etherate; In tetrahydrofuran; hexane; at -78 ℃; for 2.5h; Inert atmosphere;
DOI:10.1002/anie.201004704

Reference yield: 70.0%

: 932-31-0
ortho-tolylmagnesium bromide

: 286-20-4
cyclohexane-1,2-epoxide

: 523-25-1,6125-71-9,15315-32-9,18180-77-3,21481-86-7
(+/-)-trans-2-(2-methylphenyl)cyclohexan-1-ol

Guidance literature:: With copper(l) chloride; In tetrahydrofuran; at 0 ℃; for 2h;
DOI:10.1016/S0957-4166(00)86177-7

Reference yield:

: 63882-42-8
2-(2-methylphenyl)cyclohexanone

: 523-25-1,6125-71-9,15315-32-9,18180-77-3,21481-86-7
(+/-)-trans-2-(2-methylphenyl)cyclohexan-1-ol

Guidance literature:: With 5,5’-bis(diphenylphosphino)-4,4’-bi-1,3-benzodioxole; palladium(II) trifluoroacetate; hydrogen; toluene-4-sulfonic acid; In 2,2,2-trifluoroethanol; at 30 ℃; for 24h; under 5171.62 Torr; Autoclave; Inert atmosphere;
DOI:10.1039/d0cc00480d