Technology Process of Piperazine, 1-[2-(3-methoxyphenyl)-1-phenylethyl]-, dihydrochloride
There total 1 articles about Piperazine, 1-[2-(3-methoxyphenyl)-1-phenylethyl]-, dihydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen; acetic acid;
palladium on activated charcoal;
DOI:10.1021/jm00393a017
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 47percent aq. HBr, AcOH / 0.5 h / Heating
2: K2CO3 / methanol; H2O / 1 h / Ambient temperature
3: sodium bis(2-methoxyethoxy)aluminum hydride (Vitride) / tetrahydrofuran; toluene / 2.5 h / Ambient temperature
With
hydrogen bromide; potassium carbonate; acetic acid; sodium bis(2-methoxyethoxy)aluminium dihydride;
In
tetrahydrofuran; methanol; water; toluene;
DOI:10.1021/jm00393a017
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 47percent aq. HBr, AcOH / 0.5 h / Heating
2: 89 percent / K2CO3 / methanol; H2O / 1 h / Ambient temperature
3: sodium bis(2-methoxyethoxy)aluminum hydride (Vitride) / tetrahydrofuran; toluene / 2.5 h / Ambient temperature
With
hydrogen bromide; potassium carbonate; acetic acid; sodium bis(2-methoxyethoxy)aluminium dihydride;
In
tetrahydrofuran; methanol; water; toluene;
DOI:10.1021/jm00393a017
