4-Chloro-6-(2-phenylethyl)pyrimidin-2-amine

Base Information

Chemical Name:4-Chloro-6-(2-phenylethyl)pyrimidin-2-amine
CAS No.:6621-72-3
Molecular Formula:C12H12ClN3
Molecular Weight:233.7
Hs Code.:
NSC Number:56273
DSSTox Substance ID:DTXSID50288513
Wikidata:Q82024951

Synonyms:6621-72-3;4-chloro-6-phenethylpyrimidin-2-amine;4-chloro-6-(2-phenylethyl)pyrimidin-2-amine;NSC56273;SCHEMBL3715977;DTXSID50288513;NSC 56273;NSC-56273;A1-59531

Suppliers and Price of 4-Chloro-6-(2-phenylethyl)pyrimidin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 4-Chloro-6-(2-phenylethyl)pyrimidin-2-amine

Chemical Property:

Vapor Pressure:1.1E-06mmHg at 25°C
Boiling Point:402.4°Cat760mmHg
Flash Point:197.2°C
Density:1.272g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:233.0719751
Heavy Atom Count:16
Complexity:206

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CCC2=CC(=NC(=N2)N)Cl

Technology Process of 4-Chloro-6-(2-phenylethyl)pyrimidin-2-amine

There total 2 articles about 4-Chloro-6-(2-phenylethyl)pyrimidin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6951-49-1
2-amino-6-(2-phenylethyl)-4(1H)-pyrimidinone

: 6621-72-3
4-chloro-6-phenethyl-pyrimidin-2-ylamine

Guidance literature:: With trichlorophosphate; at 130 ℃; for 2h;

Reference yield:

: 6621-72-3
4-chloro-6-phenethyl-pyrimidin-2-ylamine

Guidance literature:: 2-Amino-4-hydroxy-6-phenaethyl-pyrimidin, POCl3;
DOI:10.1021/jo01052a055

Reference yield:

: 1252554-82-7
1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[2,3][1,4]oxazepino[5,6,7-cd]indazol-2(11H)-yl)ethan-1-one

: 6621-72-3
4-chloro-6-phenethyl-pyrimidin-2-ylamine

: 1252554-52-1
4-(1,2-dihydroindazolo[4,3-bc][1,5]benzoxazepin-4-yl)-6-(2-ph enylethyl)-2-pyrimidinamine

Guidance literature:: 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[2,3][1,4]oxazepino[5,6,7-cd]indazol-2(11H)-yl)ethan-1-one; 4-chloro-6-phenethyl-pyrimidin-2-ylamine; In 1,4-dioxane; water; for 0.166667h; Inert atmosphere of N₂;

tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; water; for 0.166667h; Inert atmosphere of N₂;

With tricyclohexylphosphine; In 1,4-dioxane; water; at 140 ℃; for 1h; Irradiation with microwave;