Technology Process of Benz(f)isoquinolin-9-ol, 1,2,3,4,4a,5,6,10b-octahydro-10b-methyl-3-(3-methyl-2-butenyl)-
There total 5 articles about Benz(f)isoquinolin-9-ol, 1,2,3,4,4a,5,6,10b-octahydro-10b-methyl-3-(3-methyl-2-butenyl)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydrogencarbonate;
In
N,N-dimethyl-formamide;
for 4h;
Heating;
DOI:10.1002/ardp.19823150108
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 97 percent / acetone / 15 h / Ambient temperature
2: aq. NaOH, NaBH4 / methanol / 0.5 h
3: 71 percent / 48percent HBr / acetic acid / 12 h / Heating
4: H2, aq. HCl / 10percent Pd/C / ethanol / 96 h / Ambient temperature
5: 55 percent / NaHCO3 / dimethylformamide / 4 h / Heating
With
hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; hydrogen bromide; hydrogen; sodium hydrogencarbonate;
palladium on activated charcoal;
In
methanol; ethanol; acetic acid; N,N-dimethyl-formamide; acetone;
DOI:10.1002/ardp.19823150108
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 71 percent / 48percent HBr / acetic acid / 12 h / Heating
2: H2, aq. HCl / 10percent Pd/C / ethanol / 96 h / Ambient temperature
3: 55 percent / NaHCO3 / dimethylformamide / 4 h / Heating
With
hydrogenchloride; hydrogen bromide; hydrogen; sodium hydrogencarbonate;
palladium on activated charcoal;
In
ethanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1002/ardp.19823150108
