4-(1,3-Dioxo-2-azaspiro[4.4]nonan-2-yl)benzoic acid

Base Information

Chemical Name:4-(1,3-Dioxo-2-azaspiro[4.4]nonan-2-yl)benzoic acid
CAS No.:61343-21-3
Molecular Formula:C15H15NO4
Molecular Weight:273.28400
Hs Code.:
DSSTox Substance ID:DTXSID90492314
Wikidata:Q82338101

Synonyms:61343-21-3;4-(1,3-Dioxo-2-azaspiro[4.4]nonan-2-yl)benzoic acid;Benzoic acid, 4-(1,3-dioxo-2-azaspiro[4.4]non-2-yl)-;DTXSID90492314

Suppliers and Price of 4-(1,3-Dioxo-2-azaspiro[4.4]nonan-2-yl)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-(1,3-Dioxo-2-azaspiro[4.4]nonan-2-yl)benzoic acid

Chemical Property:

PSA：74.68000
LogP:2.27350
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:273.10010796
Heavy Atom Count:20
Complexity:445

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC2(C1)CC(=O)N(C2=O)C3=CC=C(C=C3)C(=O)O

Technology Process of 4-(1,3-Dioxo-2-azaspiro[4.4]nonan-2-yl)benzoic acid

There total 2 articles about 4-(1,3-Dioxo-2-azaspiro[4.4]nonan-2-yl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.6%

: 62953-73-5
1-(carboxymethyl)cyclopentanecarboxylic acid

: 150-13-0,159246-81-8,8014-65-1
4-amino-benzoic acid

: 61343-21-3
4-(3-spirocyclopentanepyrrolidine-2,5-dion-1-yl)benzoic acid

Guidance literature:: In water; at 190 - 200 ℃; for 1.5h;

Reference yield:

: 61343-21-3
4-(3-spirocyclopentanepyrrolidine-2,5-dion-1-yl)benzoic acid

Guidance literature:: 2-Oxospiro<4.4>nonan-1,3-dion, entspr. Amin;

Reference yield: 78.0%

: 61343-21-3
4-(3-spirocyclopentanepyrrolidine-2,5-dion-1-yl)benzoic acid

: 100-46-9
benzylamine

: N-benzyl-4-(1,3-dioxo-2-aza-spiro[4.4]non-2-yl)-benzamide

Guidance literature:: 4-(3-spirocyclopentanepyrrolidine-2,5-dion-1-yl)benzoic acid; With 1,1'-carbonyldiimidazole; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

benzylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;