(NE)-N-(4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-ylidene)hydroxylamine

Base Information

• Chemical Name: (NE)-N-(4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-ylidene)hydroxylamine
• CAS No.: 61348-53-6
• Molecular Formula: C14H13NO5
• NSC Number: 286624
• Mol file: 61348-53-6.mol

Synonyms:NSC286624;SCHEMBL4034233;NSC-286624;61348-53-6

Chemical Property of (NE)-N-(4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-ylidene)hydroxylamine

Chemical Property:

• Vapor Pressure: 2.58E-09mmHg at 25°C
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 275.07937252
• Heavy Atom Count: 20
• Complexity: 435

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=NO)C2=C(C3=C(C(=C2O1)OC)OC=C3)OC
• Isomeric SMILES: CC1=C/C(=N\O)/C2=C(C3=C(C(=C2O1)OC)OC=C3)OC

Technology Process of (NE)-N-(4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-ylidene)hydroxylamine

There total 3 articles about (NE)-N-(4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-ylidene)hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

Khellin (82-02-0) → khellin oxime (61348-53-6)

Guidance literature:

Khellin; With toluene-4-sulfonic acid; In methanol; for 1h; Reflux;

With hydroxylamine hydrochloride; for 4h; Reflux;

DOI:10.1016/j.molstruc.2019.07.019

Reference yield:

→ Khellin-Oxim (61348-53-6)

Guidance literature:

Khellin (9), Hydroxylamin;

DOI:10.1021/jo00428a019

Reference yield:

→ khellin oxime (61348-53-6)

Guidance literature:

Pyron, NH2OH*HCl, sd. A.;

DOI:10.1016/S0040-4039(00)93142-3

upstream raw materials:

Khellin

Refernces

• 1、 Levashova, I. G.,Kazarinov, N. A.,Komissarenko, N. F.,Nel'zeva, L. B.. "REACTIVITY OF CARBONYL-CONTAINING DERIVATIVES OF 1-MONO- AND 1,3-DIPHENYLPROPANES. I. KINETICS OF THE OXIMATION REACTION OF FURANOCHROMONE, DIHYDROFLAVONONE, AND CHALCONE DERIVATIVES". . p. 57 - 62. Retrieved 2007/10/02.