4(1H)-Pyrimidinone, 2,3-dihydro-5-(1-piperidinylmethyl)-2-thioxo-

Base Information

• Chemical Name: 4(1H)-Pyrimidinone, 2,3-dihydro-5-(1-piperidinylmethyl)-2-thioxo-
• CAS No.: 5424-84-0
• Molecular Formula: C10H15N3OS
• Molecular Weight: 225.3106
• Hs Code.: 2933990090
• NSC Number: 12471
• DSSTox Substance ID: DTXSID30202595
• Nikkaji Number: J2.431.619J
• Mol file: 5424-84-0.mol

Synonyms:5424-84-0;5-(Piperidinomethyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone;4(1H)-Pyrimidinone, 2,3-dihydro-5-(1-piperidinylmethyl)-2-thioxo-;5-(piperidin-1-ylmethyl)-2-sulfanylidene-1H-pyrimidin-4-one;5-(Piperidinomethyl)-2-thiouracil;5-(Piperidin-1-ylmethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one;BRN 0913947;C10H15N3OS;5-(1-Piperidinylmethyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone;NSC12471;DTXSID30202595;MFCD01689082;NSC 12471;NSC-12471;AKOS005071809;BB-0052;LS-135912;CS-0359281;2-Mercapto-5-(piperidin-1-ylmethyl)pyrimidin-4-ol;J-516383;2-Thioxo-5-(piperidinomethyl)-1,2-dihydropyrimidine-4(3H)-one;5-(piperidin-1-ylmethyl)-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one;5-[(piperidin-1-yl)methyl]-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one

Chemical Property of 4(1H)-Pyrimidinone, 2,3-dihydro-5-(1-piperidinylmethyl)-2-thioxo-

Chemical Property:

• Melting Point: 224～225℃
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 83.98000
• Density: 1.29g/cm³
• LogP: 1.35630
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 225.09358328
• Heavy Atom Count: 15
• Complexity: 308

Purity/Quality:

98%min ^*data from raw suppliers

2,3-Dihydro-5-[(piperidin-1-yl)methyl]-2-thioxopyrimidin-4(1H)-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)CC2=CNC(=S)NC2=O

Technology Process of 4(1H)-Pyrimidinone, 2,3-dihydro-5-(1-piperidinylmethyl)-2-thioxo-

There total 2 articles about 4(1H)-Pyrimidinone, 2,3-dihydro-5-(1-piperidinylmethyl)-2-thioxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

piperidine (110-89-4) + 2-thiouracil (141-90-2,156-82-1) → 5-piperidinomethyl-2-thiouracil (5424-84-0)

Guidance literature:

In ethanol; for 48h; Heating;

DOI:10.1002/jhet.5570440109

Reference yield:

→ 5-piperidin-1-ylmethyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one (5424-84-0)

Guidance literature:

2-Thiouracil, Piperidin, Formalin;

Reference yield: 83.0%

5-piperidinomethyl-2-thiouracil (5424-84-0) + 1-bromomethyl-4-bromobenzene (589-15-1) → 2-p-bromobenzylthio-1-p-bromobenzyl-5-piperidinomethyluracil (932379-59-4)

Guidance literature:

5-piperidinomethyl-2-thiouracil; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

1-bromomethyl-4-bromobenzene; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Further stages.;

DOI:10.1002/jhet.5570440109

upstream raw materials:

piperidine

2-thiouracil

Downstream raw materials:

2-m-bromobenzylthio-5-piperidinomethyluracil

2-m-bromobenzylthio-1-m-bromobenzyl-5-piperidinomethyluracil

2-p-bromobenzylthio-5-piperidinomethyluracil

2-p-bromobenzylthio-1-p-bromobenzyl-5-piperidinomethyluracil

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 5424-84-0 5-(piperidinomethyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone

Send

Send

Metric Ton KG G Pound L ML

Send

Send