Butanamide, 3-hydroxy-N-phenyl-, (S)-

Base Information

Chemical Name:Butanamide, 3-hydroxy-N-phenyl-, (S)-
CAS No.:61444-22-2
Molecular Formula:C10H13NO2
Molecular Weight:179.219
Hs Code.:
DSSTox Substance ID:DTXSID90356189
Nikkaji Number:J2.982.228J
Wikidata:Q82135418

Synonyms:Butanamide, 3-hydroxy-N-phenyl-, (S)-;61444-22-2;DTXSID90356189

Suppliers and Price of Butanamide, 3-hydroxy-N-phenyl-, (S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Butanamide, 3-hydroxy-N-phenyl-, (S)-

Chemical Property:

Melting Point:105 °C
Boiling Point:390.3±25.0 °C(Predicted)
PSA：49.33000
Density:1.168±0.06 g/cm3(Predicted)
LogP:1.46900
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:179.094628657
Heavy Atom Count:13
Complexity:164

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(CC(=O)NC1=CC=CC=C1)O
Isomeric SMILES:C[C@@H](CC(=O)NC1=CC=CC=C1)O

Technology Process of Butanamide, 3-hydroxy-N-phenyl-, (S)-

There total 10 articles about Butanamide, 3-hydroxy-N-phenyl-, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 102-01-2,98624-45-4
N-phenylacetoacetamide

: 61444-22-2
(R)-3-hydroxy-N-phenylbutanamide

Guidance literature:: With hydrogen; {(RuCl[(S)-SYNPHOS])2(μ-Cl)3}[NH2Me2]; In methanol; at 50 ℃; for 1h; under 7500.6 Torr;
DOI:10.1055/s-2005-917089

Reference yield: 92.0%

: 127604-19-7
(S)-3-tert-butyldimethylsilyloxybutananilide

: 61444-22-2
(R)-3-hydroxy-N-phenylbutanamide

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; 1.) 30 min, 0 deg C, 2.) 30 min, room temp.;
DOI:10.1248/cpb.37.2952

Reference yield:

: 103-71-9
phenyl isocyanate

: 75-07-0,9002-91-9
acetaldehyde

: 31729-70-1
bis(iodozinc)methane

: 61444-22-2
(R)-3-hydroxy-N-phenylbutanamide

: 124095-27-8
(R)-3-hydroxy-N-phenylbutanamide

Guidance literature:: phenyl isocyanate; bis(iodozinc)methane; In tetrahydrofuran; at 80 ℃; for 0.5h; Inert atmosphere;

acetaldehyde; With (S)-bis(4-fluorophenyl)(1-methylpyrrolidin-2-yl)methanol; In tetrahydrofuran; toluene; at -40 ℃; for 72h; Overall yield = 45 %; Inert atmosphere;
DOI:10.1021/ol401425s