2,4-Diamino-5,6,7,8-tetrahydroquinazoline-6-carboxamide

Base Information

Chemical Name:2,4-Diamino-5,6,7,8-tetrahydroquinazoline-6-carboxamide
CAS No.:5466-45-5
Molecular Formula:C9H13N5O
Molecular Weight:207.2324
Hs Code.:
NSC Number:27375
DSSTox Substance ID:DTXSID30282690

Synonyms:5466-45-5;2,4-diamino-5,6,7,8-tetrahydroquinazoline-6-carboxamide;NSC27375;DTXSID30282690;NSC-27375

Suppliers and Price of 2,4-Diamino-5,6,7,8-tetrahydroquinazoline-6-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 2,4-Diamino-5,6,7,8-tetrahydroquinazoline-6-carboxamide

Chemical Property:

Vapor Pressure:4.61E-16mmHg at 25°C
Boiling Point:635.7°Cat760mmHg
Flash Point:338.3°C
Density:1.422g/cm³
XLogP3:-0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:207.11201006
Heavy Atom Count:15
Complexity:259

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(CC1C(=O)N)C(=NC(=N2)N)N

Technology Process of 2,4-Diamino-5,6,7,8-tetrahydroquinazoline-6-carboxamide

There total 4 articles about 2,4-Diamino-5,6,7,8-tetrahydroquinazoline-6-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 99055-14-8
2,4-dichloro-5,6,7,8-tetrahydro-quinazoline-6-carboxylic acid amide

: 5466-45-5
2,4-diamino-5,6,7,8-tetrahydro-quinazoline-6-carboxylic acid amide

Guidance literature:: With ethanol; ammonia; at 150 ℃;
DOI:10.1021/jo01093a004

Reference yield:

: 103505-09-5
4-oxo-cyclohexane-1,3-dicarboxylic acid dimethyl ester

: 5466-45-5
2,4-diamino-5,6,7,8-tetrahydro-quinazoline-6-carboxylic acid amide

Guidance literature:: Multi-step reaction with 4 steps

1: methanol. sodium methylate / Beim anschliessenden Erhitzen mit wss. NaOH

2: POCl₃

3: POCl₃ / Behandeln des Reaktionsprodukts mit NH₃ in Acetonitril

4: ethanol; NH₃ / 150 °C

With ethanol; ammonia; sodium methylate; trichlorophosphate;
DOI:10.1021/jo01093a004

Reference yield:

: 5439-88-3
2,4-dioxo-1,2,3,4,5,6,7,8-octahydro-quinazoline-6-carboxylic acid

: 5466-45-5
2,4-diamino-5,6,7,8-tetrahydro-quinazoline-6-carboxylic acid amide

Guidance literature:: Multi-step reaction with 3 steps

1: POCl₃

2: POCl₃ / Behandeln des Reaktionsprodukts mit NH₃ in Acetonitril

3: ethanol; NH₃ / 150 °C

With ethanol; ammonia; trichlorophosphate;
DOI:10.1021/jo01093a004