2-(Diphenylmethyl)thiophene

Base Information

• Chemical Name: 2-(Diphenylmethyl)thiophene
• CAS No.: 61532-53-4
• Molecular Formula: C17H14S
• Molecular Weight: 250.364
• DSSTox Substance ID: DTXSID90576047
• Nikkaji Number: J3.181.275E
• Wikidata: Q82465561
• Mol file: 61532-53-4.mol

Synonyms:61532-53-4;2-(Diphenylmethyl)thiophene;SCHEMBL1537396;DTXSID90576047

Chemical Property of 2-(Diphenylmethyl)thiophene

Chemical Property:

• XLogP3: 5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 250.08162162
• Heavy Atom Count: 18
• Complexity: 220

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)C3=CC=CS3

Technology Process of 2-(Diphenylmethyl)thiophene

There total 14 articles about 2-(Diphenylmethyl)thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

diphenyl(2-thienyl)methanol (79654-37-8) → (2-thienyl)diphenylmethane (61532-53-4)

Guidance literature:

With lithium aluminium tetrahydride; aluminium trichloride; In diethyl ether; for 16h; Heating;

DOI:10.1007/BF00809768

Reference yield: 89.0%

thiophene boronic acid (6165-68-0) + 1,1-Diphenylmethanol (91-01-0) → (2-thienyl)diphenylmethane (61532-53-4)

Guidance literature:

With copper(II) bis(trifluoromethanesulfonate); In chlorobenzene; at 80 ℃; for 8h; Schlenk technique; Sealed tube; Inert atmosphere;

DOI:10.3762/bjoc.12.49

Reference yield: 85.0%

thiophene (188290-36-0,8014-23-1,25233-34-5) + benzhydryl acetate (954-67-6) → (2-thienyl)diphenylmethane (61532-53-4)

Guidance literature:

With palladium dichloride; In 1,2-dichloro-ethane; at 80 ℃; for 20h; Sealed tube;

DOI:10.1039/c1cc10953g

upstream raw materials:

thiophene

1,1-Diphenylmethanol

ethyl diphenylmethyl ether

diphenyl-2-thiophenyl acetic acid

Downstream raw materials:

ethyl (R)-(5-diphenylmethylthiophen-2-yl)hydroxyacetate