18-deoxyaldosterone

Base Information

Chemical Name:18-deoxyaldosterone
CAS No.:2507-88-2
Molecular Formula:C₂₁H₂₈O₄
Molecular Weight:344.451
Hs Code.:
Mol file:2507-88-2.mol

Synonyms:Pregn-4-ene-3,20-dione,11b,18-epoxy-21-hydroxy- (7CI,8CI);Progesterone, 11b,18-epoxy-21-hydroxy-(6CI); 11,13-(Epoxymethano)-13H-cyclopenta[a]phenanthrene,pregn-4-ene-3,20-dione deriv.; 18-Deoxyaldosterone

Suppliers and Price of 18-deoxyaldosterone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 18-deoxyaldosterone

Chemical Property:

Vapor Pressure:8.77E-14mmHg at 25°C
Boiling Point:537.2°Cat760mmHg
Flash Point:190.4°C
PSA：63.60000
Density:1.25g/cm³
LogP:2.68470

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 18-deoxyaldosterone

There total 5 articles about 18-deoxyaldosterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2383-67-7,86698-81-9
11β,18,21-trihydroxy-5-pregnene-3,20-dione 3,20-di-(ethylene glycol) ketal

: 2507-88-2,2604-35-5
(+/-)-3,20-Dioxo-11β,18-oxido-21-hydroxy-regn-4-en; rac. 18-Desoxy-aldosteron

Guidance literature:: Multi-step reaction with 2 steps

1: p-toluenesulfonic acid / CH₂Cl₂ / 0.67 h / Heating

2: acetic acid / 1.33 h / Heating

With toluene-4-sulfonic acid; In dichloromethane; acetic acid;
DOI:10.1016/0040-4020(82)80058-6

Reference yield:

: 86698-82-0
11β,21-dihydroxy-5-pregnene-3,20-dione-18-oic acid 3,20-di-(ethylene glycol)ketal(18<*>11) lactone

: 2507-88-2,2604-35-5
(+/-)-3,20-Dioxo-11β,18-oxido-21-hydroxy-regn-4-en; rac. 18-Desoxy-aldosteron

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) 70percent SAMH, 2.) 10percent aq NaOH / 1.) benzene, reflux, 1 h

2: p-toluenesulfonic acid / CH₂Cl₂ / 0.67 h / Heating

3: acetic acid / 1.33 h / Heating

With sodium hydroxide; toluene-4-sulfonic acid; In dichloromethane; acetic acid;
DOI:10.1016/0040-4020(82)80058-6