5-Methyl-N-(3-(trifluoromethyl)phenyl)isoxazole-4-carboxamide

Base Information

Chemical Name:5-Methyl-N-(3-(trifluoromethyl)phenyl)isoxazole-4-carboxamide
CAS No.:61643-23-0
Molecular Formula:C12H9F3N2O2
Molecular Weight:270.20700
Hs Code.:2934990002
European Community (EC) Number:642-277-6
UNII:G7D26R0ANW
DSSTox Substance ID:DTXSID40210661
Nikkaji Number:J1.867.120D
Wikidata:Q27278888
Mol file:61643-23-0.mol

Synonyms:61643-23-0;5-Methyl-N-(3-(trifluoromethyl)phenyl)isoxazole-4-carboxamide;Leflunomide 3-Isomer;5-methyl-N-[3-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide;UNII-G7D26R0ANW;G7D26R0ANW;Leflunomide impurity C [EP];5-methyl-N-[3-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide;4-Isoxazolecarboxamide, 5-methyl-N-(3-(trifluoromethyl)phenyl)-;5-Methyl-N-[3-(trifluoromethyl)phenyl]isoxazole-4-carboxamide;Leflunomide Imp. C (EP);Leflunomide USP Related Compound C;Leflunomide USP RC C;Leflunomide Related Compound C;Leflunomide Impurity C;SCHEMBL3673039;DTXSID40210661;KBFQQKBZIFSAMY-UHFFFAOYSA-N;AKOS027585600;FT-0670757;LEFLUNOMIDE IMPURITY C [EP IMPURITY];Q27278888;N-[3-(Trifluoromethyl)phenyl]-5-methylisoxazole-4-carboxamide

Suppliers and Price of 5-Methyl-N-(3-(trifluoromethyl)phenyl)isoxazole-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Leflunomide3-Isomer
5mg
$ 160.00

Sigma-Aldrich
Leflunomide Related Compound C United States Pharmacopeia (USP) Reference Standard
10mg
$ 1160.00

American Custom Chemicals Corporation
LEFLUNOMIDE-3 95.00%
5MG
$ 497.29

Total 18 raw suppliers

Chemical Property of 5-Methyl-N-(3-(trifluoromethyl)phenyl)isoxazole-4-carboxamide

Chemical Property:

Melting Point:106 - 110℃
PSA：58.62000
LogP:3.63810
Storage Temp.:Refrigerator, under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:270.06161202
Heavy Atom Count:19
Complexity:335

Purity/Quality:

99%, ^*data from raw suppliers

Leflunomide3-Isomer ^*data from reagent suppliers

Safty Information:

Pictogram(s): 1083122
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=NO1)C(=O)NC2=CC=CC(=C2)C(F)(F)F
Uses Leflunomide analogue, with potential antiinflammatory and anti-viral activity. Leflunomide (L322750) Impurity E. Leflunomide 3-Isomer (Leflunomide EP Impurity C) is a Leflunomide analogue, with potential antiinflammatory and anti-viral activity. Leflunomide (L322750) Impurity E.

Technology Process of 5-Methyl-N-(3-(trifluoromethyl)phenyl)isoxazole-4-carboxamide

There total 1 articles about 5-Methyl-N-(3-(trifluoromethyl)phenyl)isoxazole-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: