1-[(4-Chlorophenyl)methyl]pyrrolidin-3-amine

Base Information

Chemical Name:1-[(4-Chlorophenyl)methyl]pyrrolidin-3-amine
CAS No.:61695-07-6
Molecular Formula:C11H15ClN2
Molecular Weight:210.706
Hs Code.:
DSSTox Substance ID:DTXSID60585727

Synonyms:1-[(4-Chlorophenyl)methyl]pyrrolidin-3-amine;61695-07-6;1-(4-chlorobenzyl)pyrrolidin-3-amine;SCHEMBL4427076;DTXSID60585727;MFCD09026520;AKOS010080128;EN300-1219473;F1908-1869

Suppliers and Price of 1-[(4-Chlorophenyl)methyl]pyrrolidin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(4-CHLOROBENZYL)PYRROLIDIN-3-AMINE 95.00%
5MG
$ 504.27

Total 0 raw suppliers

Chemical Property of 1-[(4-Chlorophenyl)methyl]pyrrolidin-3-amine

Chemical Property:

PSA：29.26000
LogP:2.51120
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:210.0923762
Heavy Atom Count:14
Complexity:178

Purity/Quality:: 1-(4-CHLOROBENZYL)PYRROLIDIN-3-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CC1N)CC2=CC=C(C=C2)Cl

Technology Process of 1-[(4-Chlorophenyl)methyl]pyrrolidin-3-amine

There total 2 articles about 1-[(4-Chlorophenyl)methyl]pyrrolidin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 226248-99-3
3-{(tert-butoxycarbonyl)amino}-1-(4-chlorobenzyl)-pyrrolidine

: 61695-07-6
3-amino-1-p-chlorophenylmethylpyrrolidine

Guidance literature:: With trifluoroacetic acid;
DOI:10.1016/j.bmcl.2004.08.009

Reference yield:

: 622-95-7
4-chlorobenzyl bromide

: 61695-07-6
3-amino-1-p-chlorophenylmethylpyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 40 °C

2: hydrogenchloride / 1,4-dioxane; methanol / 1 h / 20 °C

With hydrogenchloride; potassium carbonate; In 1,4-dioxane; methanol; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.0c01026

Reference yield:

: 27115-49-7
N-(3-Methylbenzoyl)glycine

: 61695-07-6
3-amino-1-p-chlorophenylmethylpyrrolidine

: N-{[1-(4-chloro-benzyl)-pyrrolidin-3-ylcarbamoyl]-methyl}-3-methyl-benzamide

Guidance literature:: With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine;
DOI:10.1016/j.bmcl.2004.08.009