Ethyl 2-(3-methylbenzyl)-3-oxobutanoate

Base Information

• Chemical Name: Ethyl 2-(3-methylbenzyl)-3-oxobutanoate
• CAS No.: 61713-38-0
• Molecular Formula: C14H18O3
• Molecular Weight: 234.29100

Synonyms:2-(3-methyl-benzyl)-acetoacetic acid ethyl ester;Ethyl-α-(3-methylbenzyl)acetoacetat;ethyl 2-(m-tolylmethyl)-3-oxo-butanoate;2-(3-Methyl-benzyl)-acetessigsaeure-aethylester;

Chemical Property of Ethyl 2-(3-methylbenzyl)-3-oxobutanoate

Chemical Property:

• PSA: 43.37000
• LogP: 2.30580

Purity/Quality:

99% ，98% ^*data from raw suppliers

Ethyl 2-(3-methylbenzyl)-3-oxobutanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethyl 2-(3-methylbenzyl)-3-oxobutanoate

There total 3 articles about Ethyl 2-(3-methylbenzyl)-3-oxobutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

1-bromomethyl-3-methyl-benzene (620-13-3) + ethyl acetoacetate (141-97-9) → ethyl 2-(3-methylbenzyl)-3-oxobutanoate (61713-38-0)

Guidance literature:

ethyl acetoacetate; With potassium tert-butylate; In tetrahydrofuran; tert-butyl alcohol; at 0 ℃; for 0.5h; Inert atmosphere;

1-bromomethyl-3-methyl-benzene; In tetrahydrofuran; tert-butyl alcohol; at 0 - 70 ℃; Inert atmosphere;

DOI:10.1002/cmdc.201000490

Reference yield:

1-chloromethyl-3-methyl-benzene (620-19-9) + ethyl acetoacetate (141-97-9) → ethyl 2-(3-methylbenzyl)-3-oxobutanoate (61713-38-0)

Guidance literature:

ethyl acetoacetate; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 0.5h;

1-chloromethyl-3-methyl-benzene; In tetrahydrofuran; mineral oil; Reflux;

DOI:10.1016/j.bmc.2021.116033

Reference yield:

→ ethyl 2-(3-methylbenzyl)-3-oxobutanoate (61713-38-0)

Guidance literature:

upstream raw materials:

1-bromomethyl-3-methyl-benzene

ethyl acetoacetate

1-chloromethyl-3-methyl-benzene

Downstream raw materials:

6-methyl-5-(3-methyl-benzyl)-pyrimidine-2,4-diyldiamine

C₁₈H₂₁N₃O₄S

C₁₈H₁₈N₂O

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 61713-38-0 Ethyl 2-(3-methylbenzyl)-3-oxobutanoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send