5-chloro-N-{[5-(5-chloro-1,3-benzoxazol-2-yl)-2-methylphenyl]carbamothioyl}-2-methoxybenzamide

Base Information

Chemical Name:5-chloro-N-{[5-(5-chloro-1,3-benzoxazol-2-yl)-2-methylphenyl]carbamothioyl}-2-methoxybenzamide
CAS No.:6451-05-4
Molecular Formula:C23H17Cl2N3O3S
Molecular Weight:247.253
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40387640
Wikidata:Q82182013
Mol file:6451-05-4.mol

Synonyms:STK163954;5-chloro-N-{[5-(5-chloro-1,3-benzoxazol-2-yl)-2-methylphenyl]carbamothioyl}-2-methoxybenzamide;DTXSID40387640;AKOS003258408

Suppliers and Price of 5-chloro-N-{[5-(5-chloro-1,3-benzoxazol-2-yl)-2-methylphenyl]carbamothioyl}-2-methoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 5-chloro-N-{[5-(5-chloro-1,3-benzoxazol-2-yl)-2-methylphenyl]carbamothioyl}-2-methoxybenzamide

Chemical Property:

PSA：119.01000
Density:1.438g/cm³
LogP:7.04070
XLogP3:6.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:485.0367680
Heavy Atom Count:32
Complexity:687

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C=C(C=C1)C2=NC3=C(O2)C=CC(=C3)Cl)NC(=S)NC(=O)C4=C(C=CC(=C4)Cl)OC

Technology Process of 5-chloro-N-{[5-(5-chloro-1,3-benzoxazol-2-yl)-2-methylphenyl]carbamothioyl}-2-methoxybenzamide

There total 2 articles about 5-chloro-N-{[5-(5-chloro-1,3-benzoxazol-2-yl)-2-methylphenyl]carbamothioyl}-2-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 2348-81-4
2-amino-1,4-naphthoquinone

: 88284-48-4
2-(trimethylsilyl)phenyl trifluoromethanesulfonate

: 6451-05-4
5H-benzo[b]carbazole-6,11-dione

Guidance literature:: With tetrabutylammonium triphenyldifluorosilicate; In tetrahydrofuran; at 25 ℃; for 6h; Inert atmosphere;
DOI:10.1021/acs.orglett.6b01090

Reference yield:

: 2348-81-4
2-amino-1,4-naphthoquinone

: 88284-48-4
2-(trimethylsilyl)phenyl trifluoromethanesulfonate

: 56568-51-5
5-phenyl-5H-benzo[b]carbazole-6,11-dione

: 6451-05-4
5H-benzo[b]carbazole-6,11-dione

: 56176-17-1
2-amino-3-phenylnaphthalene-1,4-dione

Guidance literature:: With 18-crown-6 ether; cesium fluoride; In tetrahydrofuran; at 25 ℃; for 6h; Inert atmosphere;
DOI:10.1021/acs.orglett.6b01090