(R)-2-Hydroxy-2-phenylpropanoic acid

Base Information

Chemical Name:(R)-2-Hydroxy-2-phenylpropanoic acid
CAS No.:3966-30-1
Molecular Formula:C9H10 O3
Molecular Weight:166.177
Hs Code.:2918199090
UNII:H38DKR9931
Nikkaji Number:J74.193K
Wikidata:Q27279587
Mol file:3966-30-1.mol

Synonyms:3966-30-1;(R)-2-HYDROXY-2-PHENYLPROPANOIC ACID;(R)-(-)-2-HYDROXY-2-PHENYLPROPIONIC ACID;(2R)-2-hydroxy-2-phenylpropanoic acid;Atrolactic acid, (-)-;H38DKR9931;UNII-H38DKR9931;2-Hydroxy-2-phenylpropanoic acid #;(r)-atrolactic acid;(-)-atrolactic acid;r-(-)-atrolactic acid;(R)-phenyl lactic acid;(R)-alpha-Hydroxy-alpha-methylbenzeneacetic acid;SCHEMBL198241;Benzeneacetic acid, alpha-hydroxy-alpha-methyl-, (R)-;(R)-2-PHENYLLACTIC ACID;(R)-(-)-ATROLACTIC ACID;MFCD00067699;AB02735;AS-62946;(R)-2-HYDROXY-2-PHENYLPROPANOICACID;CS-0452105;EN300-72764;D78562;Q27279587;(R)-(-)-2-hydroxy-2-phenylpropionic acid, AldrichCPR;Benzeneacetic acid, .alpha.-hydroxy-.alpha.-methyl-, (R)-;BENZENEACETIC ACID, .ALPHA.-HYDROXY-.ALPHA.-METHYL-, (.ALPHA.R)-

Suppliers and Price of (R)-2-Hydroxy-2-phenylpropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-(+)-2-Hydroxy-2-phenylpropionicAcid
250mg
$ 330.00

American Custom Chemicals Corporation
(R)-(-)-2-HYDROXY-2-PHENYL PROPIONIC ACID 95.00%
1G
$ 2032.80

Alfa Aesar
(R)-(-)-2-Hydroxy-2-phenylpropionic acid, 98+%
1g
$ 278.00

Alfa Aesar
(R)-(-)-2-Hydroxy-2-phenylpropionic acid, 98+%
250mg
$ 86.40

AHH
(R)-(-)-2-Hydroxy-2-phenylpropionicacid 98%
5g
$ 625.00

Total 12 raw suppliers

Chemical Property of (R)-2-Hydroxy-2-phenylpropanoic acid

Chemical Property:

Vapor Pressure:8.3E-05mmHg at 25°C
Melting Point:112 °C
Refractive Index:1.5500 (estimate)
Boiling Point:327.2°Cat760mmHg
PKA:3.53±0.25(Predicted)
Flash Point:165.9°C
PSA：57.53000
Density:1.261g/cm³
LogP:0.97870
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:166.062994177
Heavy Atom Count:12
Complexity:173

Purity/Quality:

97% ^*data from raw suppliers

(S)-(+)-2-Hydroxy-2-phenylpropionicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=CC=C1)(C(=O)O)O
Isomeric SMILES:C[C@@](C1=CC=CC=C1)(C(=O)O)O
Uses It is used in the asymmetric synthesis. Part III. Stereospecific synthesis of (R)-2-hydroxy-2-phenylpropionic acid, and (R)- and (S)-2-cyclohexyl-2-hydroxy-2-phenylacetic acid. Configurational relationship between (R)(-)-2-hydroxy-2-phenylpropionic acid and (S)(+)-2-phenylpropionic acid.

Technology Process of (R)-2-Hydroxy-2-phenylpropanoic acid

There total 67 articles about (R)-2-Hydroxy-2-phenylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 57133-37-6,57133-40-1
phenyl-2 hydroxy-2 propanoate de (-) menthyle

: 3966-30-1
(R)-Atrolactic acid

Guidance literature:: With potassium hydroxide; water; In methanol; for 4h; Heating;
DOI:10.1016/S0040-4020(01)89110-9

Reference yield: 62.0%

: 110457-29-9
(S)-2-hydroxymethyl-N-((R)-2-hydroxy-2-phenyl)propanoylpyrrolidine

: 3966-30-1
(R)-Atrolactic acid

Guidance literature:: With sulfuric acid; In water; at 90 ℃; for 0.5h;
DOI:10.1016/S0040-4020(98)00914-4

Reference yield: 60.0%

: 1-(4-methyl-[1,3]dioxan-2-yl)-1-phenyl-ethanol

: 3966-30-1
(R)-Atrolactic acid

Guidance literature:: 1-(4-methyl-[1,3]dioxan-2-yl)-1-phenyl-ethanol; With ozone; In dichloromethane; at 20 ℃; for 1h;

With sodium hydroxide; In methanol; water; Further stages.;
DOI:10.1021/ol015914k