Benzamide, 4-(dimethylamino)-N-[[4-(hydroxymethyl)phenyl]methyl]-

Base Information

Chemical Name:Benzamide, 4-(dimethylamino)-N-[[4-(hydroxymethyl)phenyl]methyl]-
CAS No.:617691-18-6
Molecular Formula:C17H20N2O2
Molecular Weight:284.358
Hs Code.:

Synonyms:Benzamide,4-(dimethylamino)-N-[[4-(hydroxymethyl)phenyl]methyl];4-dimethylamino-N-(4-hydroxymethylbenzyl)benzamide;

Suppliers and Price of Benzamide, 4-(dimethylamino)-N-[[4-(hydroxymethyl)phenyl]methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzamide, 4-(dimethylamino)-N-[[4-(hydroxymethyl)phenyl]methyl]-

Chemical Property:

PSA：52.57000
LogP:2.56580

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzamide, 4-(dimethylamino)-N-[[4-(hydroxymethyl)phenyl]methyl]-

There total 3 articles about Benzamide, 4-(dimethylamino)-N-[[4-(hydroxymethyl)phenyl]methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 39895-56-2
4-hydroxymethyl-benzylamine

: 617691-18-6
4-(dimethylamino)-N-(4-hydroxymethylbenzyl)benzamide

Guidance literature:: p-N,N-dimethylaminobenzoic acid; With bis(2-oxo-1,3-oxazolidin-3-yl)phosphinous chloride; triethylamine; In dichloromethane; at 0 - 20 ℃; for 0.333333h;

4-hydroxymethyl-benzylamine; With triethylamine; In dichloromethane; at 20 ℃;

Reference yield:

: 39895-56-2
4-hydroxymethyl-benzylamine

: C₁₅H₁₈N₃O₇P

: 617691-18-6
4-(dimethylamino)-N-(4-hydroxymethylbenzyl)benzamide

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃;
DOI:10.1021/jm030377q

Reference yield:

: 619-84-1
p-N,N-dimethylaminobenzoic acid

: 617691-18-6
4-(dimethylamino)-N-(4-hydroxymethylbenzyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / 0.33 h / 20 °C

2: Et₃N / CH₂Cl₂ / 20 °C

With triethylamine; In dichloromethane;
DOI:10.1021/jm030377q