1-Ethynyl-2,3,5,6-tetrafluoro-4-methylbenzene

Base Information

Chemical Name:1-Ethynyl-2,3,5,6-tetrafluoro-4-methylbenzene
CAS No.:61794-58-9
Molecular Formula:C₉H₄F₄
Molecular Weight:188.124
Hs Code.:
DSSTox Substance ID:DTXSID90708503
Wikidata:Q82642864

Synonyms:1-Ethynyl-2,3,5,6-tetrafluoro-4-methylbenzene;61794-58-9;SCHEMBL16627103;DTXSID90708503

Suppliers and Price of 1-Ethynyl-2,3,5,6-tetrafluoro-4-methylbenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Ethynyl-2,3,5,6-tetrafluoro-4-methylbenzene

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:188.02491278
Heavy Atom Count:13
Complexity:215

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=C(C(=C1F)F)C#C)F)F

Technology Process of 1-Ethynyl-2,3,5,6-tetrafluoro-4-methylbenzene

There total 3 articles about 1-Ethynyl-2,3,5,6-tetrafluoro-4-methylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 61794-48-7
3-(2,3,5,6-Tetrafluoro-4-methyl-phenyl)-prop-2-yn-1-ol

: 61794-58-9
4-Methyltetrafluorphenylacetylen

Guidance literature:: With nickel(IV) oxide; sodium hydroxide; In 1,4-dioxane; at 50 ℃;
DOI:10.1016/0040-4020(76)85181-2

Reference yield:

: 61794-44-3
1,2,4,5-Tetrafluoro-3-jodo-6-methylbenzol

: 61794-58-9
4-Methyltetrafluorphenylacetylen

Guidance literature:: Multi-step reaction with 2 steps

1: (i) CuI, aq. NH₃, EtOH, (ii) /BRN= 2050272/, Py, (iii) H₂SO₄, MeOH

2: NiO₂, aq. NaOH / dioxane / 50 °C

With nickel(IV) oxide; sodium hydroxide; In 1,4-dioxane;
DOI:10.1016/0040-4020(76)85181-2

Reference yield:

: 4232-72-8
2,3,5,6-Tetrafluor-4-methylphenylhydrazin

: 61794-58-9
4-Methyltetrafluorphenylacetylen

Guidance literature:: Multi-step reaction with 3 steps

1: MeI, Ag₂O

2: (i) CuI, aq. NH₃, EtOH, (ii) /BRN= 2050272/, Py, (iii) H₂SO₄, MeOH

3: NiO₂, aq. NaOH / dioxane / 50 °C

With nickel(IV) oxide; sodium hydroxide; silver(l) oxide; methyl iodide; In 1,4-dioxane;
DOI:10.1016/0040-4020(76)85181-2