Benzene, [3-[(trifluoromethyl)sulfonyl]propyl]-

Base Information

• Chemical Name: Benzene, [3-[(trifluoromethyl)sulfonyl]propyl]-
• CAS No.: 61795-10-6
• Molecular Formula: C10H11F3O2S
• Molecular Weight: 252.257
• Mol file: 61795-10-6.mol

Synonyms:Benzene,[3-[(trifluoromethyl)sulfonyl]propyl];3-triflylpropylbenzene;3-(trifluoromethylsulfonyl)-propyl-benzene;

Chemical Property of Benzene, [3-[(trifluoromethyl)sulfonyl]propyl]-

Chemical Property:

• Boiling Point: 320.7±42.0 °C(Predicted)
• PSA: 42.52000
• Density: 1.309±0.06 g/cm3(Predicted)
• LogP: 3.63460

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, [3-[(trifluoromethyl)sulfonyl]propyl]-

There total 4 articles about Benzene, [3-[(trifluoromethyl)sulfonyl]propyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(3-phenylpropyl)(trifluoromethyl)thioether → (3-((trifluoromethyl)sulfonyl)propyl)benzene (61795-10-6)

Guidance literature:

With dihydrogen peroxide; acetic acid; In water; at 80 - 90 ℃;

DOI:10.1039/c4ob00403e

Reference yield: 75.0%

1-Bromo-3-phenylpropane (637-59-2) + Langlois reagent (2926-29-6) → (3-((trifluoromethyl)sulfonyl)propyl)benzene (61795-10-6)

Guidance literature:

In N,N-dimethyl-formamide; at 100 ℃; for 24h;

DOI:10.1021/acs.orglett.8b02483

Reference yield:

1-Bromo-3-phenylpropane (637-59-2) → (3-((trifluoromethyl)sulfonyl)propyl)benzene (61795-10-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium fluoride / acetonitrile / 15 h / 110 °C / Sealed tube

2: dihydrogen peroxide; acetic acid / water / 80 - 90 °C

With potassium fluoride; dihydrogen peroxide; acetic acid; In water; acetonitrile;

DOI:10.1039/c4ob00403e

upstream raw materials:

1-Bromo-3-phenylpropane

Langlois reagent

Downstream raw materials:

3-phenyl-propionaldehyde