(2S)-1-Methyl-2-Pyrrolidineethanol

Base Information

Chemical Name:(2S)-1-Methyl-2-Pyrrolidineethanol
CAS No.:61810-78-4
Molecular Formula:C7H15NO
Molecular Weight:129.202
Hs Code.:
Mol file:61810-78-4.mol

Synonyms:N-methylhomoprolinol;InChI=1/C7H15NO/c1-8-5-2-3-7(8)4-6-9/h7,9H,2-6H2,1H;(S)-2-(1-Methylpyrrolidin-2-yl)ethanol;(-)-2-((S)-1-methylpyrrolidin-2-yl)ethanol;(S)-(-)-Methyl-2-pyrrolidineethanol;2-Pyrrolidineethanol,1-methyl;(S)-2-(2-hydroxyethyl)pyrrolidine;(S)-2-(2-hydroxyethyl)-1-methylpyrroline;2-Pyrrolidineethanol,1-methyl-,(S);

Suppliers and Price of (2S)-1-Methyl-2-Pyrrolidineethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-2-(1-Methylpyrrolidin-2-yl)ethanol
100mg
$ 265.00

J&W Pharmlab
(S)-2-(1-Methyl-pyrrolidin-2-yl)-ethanol 97%
1g
$ 698.00

Crysdot
(S)-2-(1-Methylpyrrolidin-2-yl)ethanol 95+%
1g
$ 594.00

Chemenu
(S)-2-(1-Methylpyrrolidin-2-yl)ethanol 95%
2g
$ 2417.00

Alichem
(S)-2-(1-Methylpyrrolidin-2-yl)ethanol
1g
$ 606.00

Activate Scientific
(S)-2-(1-Methyl-pyrrolidin-2-yl)-ethanol 97+% ee
1 g
$ 903.00

Total 11 raw suppliers

Chemical Property of (2S)-1-Methyl-2-Pyrrolidineethanol

Chemical Property:

Boiling Point:214.0±0.0 °C(Predicted)
PKA:15.03±0.10(Predicted)
PSA：23.47000
Density:0.958±0.06 g/cm3(Predicted)
LogP:0.40090

Purity/Quality:

97% ^*data from raw suppliers

(S)-2-(1-Methylpyrrolidin-2-yl)ethanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2S)-1-Methyl-2-Pyrrolidineethanol

There total 3 articles about (2S)-1-Methyl-2-Pyrrolidineethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 88790-37-8,132482-05-4,813433-68-0
(2S)-tert-Butyl 2-(2-methoxy-2-oxoethyl)pyrrolidine-2-carboxylate

: 61810-78-4
(-)-2-((S)-1-methylpyrrolidin-2-yl)ethanol

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether;
DOI:10.1016/S0040-4039(00)86026-8

Reference yield: 60.0%

: 56633-72-8
(-)-(S)-2-methoxycarbonylmethylpyrrolidine-1-carboxylic acid benzyl ester

: 61810-78-4
(-)-2-((S)-1-methylpyrrolidin-2-yl)ethanol

Guidance literature:: (-)-(S)-2-methoxycarbonylmethylpyrrolidine-1-carboxylic acid benzyl ester; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 45 ℃; Inert atmosphere;

With water; sodium hydroxide; In tetrahydrofuran; diethyl ether; at 0 ℃; Inert atmosphere;
DOI:10.1021/ol100627c

Reference yield:

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 61810-78-4
(-)-2-((S)-1-methylpyrrolidin-2-yl)ethanol

Guidance literature:: Multi-step reaction with 2 steps

2: 90 percent / 3 eq. LiAlH₄ / diethyl ether

With lithium aluminium tetrahydride; In diethyl ether;
DOI:10.1016/S0040-4039(00)86026-8