2-Amino-4,5-dibromobenzoic acid

Base Information

• Chemical Name: 2-Amino-4,5-dibromobenzoic acid
• CAS No.: 75057-62-4
• Molecular Formula: C7H5Br2NO2
• Molecular Weight: 294.93
• Hs Code.: 2922499990
• DSSTox Substance ID: DTXSID90407024
• Wikidata: Q72463799
• Mol file: 75057-62-4.mol

Synonyms:2-amino-4,5-dibromobenzoic acid;75057-62-4;MFCD00017100;Benzoic acid, 2-amino-4,5-dibromo-;4,5-dibromoanthranilic acid;SCHEMBL1047232;2-Amino-4,5-dibromobenzoicacid;DTXSID90407024;AKOS005203197;2-Amino-4 pound not5-dibromobenzoic acid;DS-12899;SY107668;CS-0028798;FT-0601836;AB00982133-01;A856459;SR-01000068140;SR-01000068140-1;Z89264939

Chemical Property of 2-Amino-4,5-dibromobenzoic acid

Chemical Property:

• Vapor Pressure: 1.4E-06mmHg at 25°C
• Melting Point: 228-229℃ (decomposition)
• Refractive Index: 1.699
• Boiling Point: 383.9 °C at 760 mmHg
• Flash Point: 186 °C
• PSA: 63.32000
• Density: 2.158 g/cm³
• LogP: 3.07320
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 294.86665
• Heavy Atom Count: 12
• Complexity: 188

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-4,5-dibromobenzoicacid 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=CC(=C1Br)Br)N)C(=O)O

Technology Process of 2-Amino-4,5-dibromobenzoic acid

There total 11 articles about 2-Amino-4,5-dibromobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + 4,5-dibromo-2-nitro-benzoic acid (102000-63-5) → 2-amino-4,5-dibromobenzoic acid (75057-62-4) + anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4)

Guidance literature:

Reference yield:

2-methylgramine (37125-92-1) → 2-amino-4,5-dibromobenzoic acid (75057-62-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 29.9 percent / bromine / acetic acid / 4 h / Ambient temperature; 10.6 mmol of 2-methylgramine, 15.8 mmol of bromine

2: 6.3 percent / bromine / acetic acid / 4 h / Ambient temperature

3: 36percent hydrogen peroxide/glacial acetic acid / 192 h / Ambient temperature

With dihydrogen peroxide; bromine; acetic acid; In acetic acid;

Reference yield:

4,5-dibromo-phthalamic acid (861379-12-6) → 2-amino-4,5-dibromobenzoic acid (75057-62-4)

Guidance literature:

With alkaline sodium hypochlorite; at 80 ℃;

upstream raw materials:

4,5-dibromophthalimide

4,5-dibromo-phthalamic acid

4,5-dibromo-2-nitro-benzoic acid

5,6-Dibromo-2-methylgramine

Downstream raw materials:

3,4-dibromobenzoic acid

2,4,5-tribromo-benzoic acid

3,5-dibromosalicylic acid

6,7-dibromo-2-(2-methoxy-phenoxymethyl)-benzo[d][1,3]oxazin-4-one