Cyclopentanepentanal, 5-hydroxy-3-[(tetrahydro-2H-pyran-2-yl)oxy]-2-[3-[(tetrahydro-2H-pyran- 2-yl)oxy]-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]-

Base Information

Chemical Name:Cyclopentanepentanal, 5-hydroxy-3-[(tetrahydro-2H-pyran-2-yl)oxy]-2-[3-[(tetrahydro-2H-pyran- 2-yl)oxy]-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]-
CAS No.:61903-05-7
Molecular Formula:C31H43F3O7
Molecular Weight:584.673
Hs Code.:

Cyclopentanepentanal,
5-hydroxy-3-[(tetrahydro-2H-pyran-2-yl)oxy]-2-[3-[(tetrahydro-2H-pyran-
2-yl)oxy]-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]-

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Cyclopentanepentanal, 5-hydroxy-3-[(tetrahydro-2H-pyran-2-yl)oxy]-2-[3-[(tetrahydro-2H-pyran- 2-yl)oxy]-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]-

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MSDS Files:: SDS file from LookChem

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Technology Process of Cyclopentanepentanal, 5-hydroxy-3-[(tetrahydro-2H-pyran-2-yl)oxy]-2-[3-[(tetrahydro-2H-pyran- 2-yl)oxy]-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]-

There total 3 articles about Cyclopentanepentanal, 5-hydroxy-3-[(tetrahydro-2H-pyran-2-yl)oxy]-2-[3-[(tetrahydro-2H-pyran- 2-yl)oxy]-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 73275-78-2
16-<3-(trifluoromethyl)phenoxy>-2,3,17,18,19,20-hexanorprostaglandin F_1α methyl ester 11,15αβ-bis(tetrahydropyran-2-yl ether)

: 61903-05-7
16-<3-(trifluoromethyl)phenoxy>-2,3,17,18,19,20-hexanorprost-13-en-1-al 11,15αβ-bis(tetrahydropyran-2-yl ether)

Guidance literature:: With diisobutylaluminium hydride; In toluene; at -78 ℃; for 0.5h;
DOI:10.1021/jm00179a011

Reference yield:

: 73275-77-1
(5Z,E)-16-<3-(trifluoromethyl)phenoxy>-2,3,17,18,19,20-hexanorprostaglandin F_2α 11,15αβ-bis(tetrahydropyran-2-yl ether)

: 61903-05-7
16-<3-(trifluoromethyl)phenoxy>-2,3,17,18,19,20-hexanorprost-13-en-1-al 11,15αβ-bis(tetrahydropyran-2-yl ether)

Guidance literature:: Multi-step reaction with 3 steps

1: H₂ / 5percent Pd/C / methanol / 25 °C / 760 Torr

2: diethyl ether

3: 100 percent / diisobutylaluminum hydride (DIBAL) / toluene / 0.5 h / -78 °C

With hydrogen; diisobutylaluminium hydride; palladium on activated charcoal; In methanol; diethyl ether; toluene;
DOI:10.1021/jm00179a011

Reference yield:

: 5-{(1R,2R,3R,5S)-5-Hydroxy-3-(tetrahydro-pyran-2-yloxy)-2-[(E)-(R)-3-(tetrahydro-pyran-2-yloxy)-4-(3-trifluoromethyl-phenoxy)-but-1-enyl]-cyclopentyl}-pentanoic acid

: 61903-05-7
16-<3-(trifluoromethyl)phenoxy>-2,3,17,18,19,20-hexanorprost-13-en-1-al 11,15αβ-bis(tetrahydropyran-2-yl ether)

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether

2: 100 percent / diisobutylaluminum hydride (DIBAL) / toluene / 0.5 h / -78 °C

With diisobutylaluminium hydride; In diethyl ether; toluene;
DOI:10.1021/jm00179a011