Isoquinoline, 1-[(3,4,5-trimethoxyphenyl)methyl]-

Base Information

Chemical Name:Isoquinoline, 1-[(3,4,5-trimethoxyphenyl)methyl]-
CAS No.:61972-54-1
Molecular Formula:C19H19NO3
Molecular Weight:309.365
Hs Code.:
DSSTox Substance ID:DTXSID70455568
Wikidata:Q82277637

Synonyms:61972-54-1;1-(3,4,5-Trimethoxybenzyl)isoquinoline;Isoquinoline, 1-[(3,4,5-trimethoxyphenyl)methyl]-;SCHEMBL8555054;DTXSID70455568

Suppliers and Price of Isoquinoline, 1-[(3,4,5-trimethoxyphenyl)methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Isoquinoline, 1-[(3,4,5-trimethoxyphenyl)methyl]-

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:309.13649347
Heavy Atom Count:23
Complexity:351

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1OC)OC)CC2=NC=CC3=CC=CC=C32

Technology Process of Isoquinoline, 1-[(3,4,5-trimethoxyphenyl)methyl]-

There total 4 articles about Isoquinoline, 1-[(3,4,5-trimethoxyphenyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 1-(3,4,5-Trimethoxybenzyl)-1-cyan-2-benzoyl-1,2-dihydroisochinolin

: 61972-54-1
1-(3,4,5-Trimethoxybenzyl)-isochinolin

Guidance literature:: With potassium hydroxide;
DOI:10.1002/ardp.19853180603

Reference yield:

: 1-(3,4,5-trimethoxybenzyl)isoquinoline N-oxide

: 61972-54-1
1-(3,4,5-Trimethoxybenzyl)-isochinolin

: 1-(2-hydroxy-3,4,5-trimethoxybenzyl)isoquinoline

Guidance literature:: With trifluoroacetic acid; In dichloromethane; UV-irradiation;
DOI:10.1021/jo034074f

Reference yield:

: 21852-50-6
3,4,5-trimethoxybenzyl bromide

: 61972-54-1
1-(3,4,5-Trimethoxybenzyl)-isochinolin

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / dimethylformamide / 3.5 h / 0 °C

2: 65 percent / KOH

With potassium hydroxide; In N,N-dimethyl-formamide;
DOI:10.1002/ardp.19853180603