2-(3-oxo-3-phenylpropyl)-1H-isoindole-1,3(2H)-dione

Base Information

Chemical Name:2-(3-oxo-3-phenylpropyl)-1H-isoindole-1,3(2H)-dione
CAS No.:3617-18-3
Molecular Formula:C17H13NO3
Molecular Weight:279.295
Hs Code.:
NSC Number:190759
DSSTox Substance ID:DTXSID90307338
Nikkaji Number:J437.095C
Wikidata:Q82054710
ChEMBL ID:CHEMBL1880347
Mol file:3617-18-3.mol

Synonyms:3617-18-3;2-(3-oxo-3-phenylpropyl)-1H-isoindole-1,3(2H)-dione;2-(3-oxo-3-phenylpropyl)isoindole-1,3-dione;MLS003106984;NSC190759;Oprea1_749317;SCHEMBL729028;CHEMBL1880347;DTXSID90307338;NSC-190759;SMR001821865

Suppliers and Price of 2-(3-oxo-3-phenylpropyl)-1H-isoindole-1,3(2H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-(3-oxo-3-phenylpropyl)-1H-isoindole-1,3(2H)-dione

Chemical Property:

Vapor Pressure:1.16E-08mmHg at 25°C
Boiling Point:460.5°Cat760mmHg
Flash Point:213.5°C
Density:1.292g/cm³
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:279.08954328
Heavy Atom Count:21
Complexity:415

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)CCN2C(=O)C3=CC=CC=C3C2=O

Technology Process of 2-(3-oxo-3-phenylpropyl)-1H-isoindole-1,3(2H)-dione

There total 14 articles about 2-(3-oxo-3-phenylpropyl)-1H-isoindole-1,3(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 136918-14-4,85-41-6
phthalimide

: 768-03-6,26742-84-7
Phenyl vinyl ketone

: 3617-18-3
2‐(3‐oxo‐3‐phenylpropyl)isoindoline‐1,3‐dione

Guidance literature:: With sodium methylate; In dimethyl sulfoxide; for 2h; Ambient temperature;
DOI:10.1080/00397919108055448

Reference yield: 87.0%

: 17564-64-6
N-(chloromethyl)phthalimide

: 66324-10-5
tert-butyldimethyl(1-phenylvinyloxy)silane

: 3617-18-3
2‐(3‐oxo‐3‐phenylpropyl)isoindoline‐1,3‐dione

Guidance literature:: N-(chloromethyl)phthalimide; tert-butyldimethyl(1-phenylvinyloxy)silane; With 2,6-dimethylpyridine; potassium 5-bromo-1H-indole-1-carbodithioate; In 1,2-dichloro-ethane; at 25 ℃; for 24h; Schlenk technique; Inert atmosphere; Irradiation;

With trifluoroacetic acid; In chloroform; 1,2-dichloro-ethane; Schlenk technique; Inert atmosphere;
DOI:10.1002/anie.201915814

Reference yield: 83.0%

: 13735-81-4
1-styrenyloxytrimethylsilane

: 616883-83-1
O-phthalimidomethyl trichloroacetamidate

: 3617-18-3
2‐(3‐oxo‐3‐phenylpropyl)isoindoline‐1,3‐dione

Guidance literature:: With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 20 ℃; for 0.333333h;
DOI:10.1016/j.tet.2004.04.011