Methyl 3-cyclopropylpropanoate

Base Information

• Chemical Name: Methyl 3-cyclopropylpropanoate
• CAS No.: 62021-34-5
• Molecular Formula: C7H12O2
• Molecular Weight: 128.171
• Mol file: 62021-34-5.mol

Synonyms:Cyclopropanepropanoic acid,methyl ester;

Chemical Property of Methyl 3-cyclopropylpropanoate

Chemical Property:

• Boiling Point: 157.8±8.0 °C(Predicted)
• PSA: 26.30000
• Density: 1.006±0.06 g/cm3(Predicted)
• LogP: 1.34960

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 3-cyclopropylpropanoate

There total 2 articles about Methyl 3-cyclopropylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

7-cyclopropylmercuric bromide (83020-41-1) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → 3-Cyclopropyl-propionic acid methyl ester (62021-34-5)

Guidance literature:

With sodium tetrahydroborate; In dichloromethane; Mechanism; Ambient temperature; reaction with other alkenes;

DOI:10.1016/S0040-4039(00)87452-3

Reference yield:

2,4,4,6-tetrachloro-hexanoic acid methyl ester (49642-18-4) → 3-Cyclopropyl-propionic acid methyl ester (62021-34-5)

Guidance literature:

With hydrogenchloride; zinc; In ethanol;

DOI:10.1007/BF00921716

Reference yield:

3-Cyclopropyl-propionic acid methyl ester (62021-34-5) → methyl 4-methylpentanoate (2412-80-8) + methyl hexanoate (106-70-7)

Guidance literature:

With hydrogen; Chromatron W; platinum; In gas; at 40 ℃; other temperatures (100 deg C, 200 deg C); hydrogenolysis of cyclopropane derivatives, effect of the nature of substituent on the product ratio; deuterolysis; reaction chromato-mass spectrometry for studiyng of cyclopropane compounds;

DOI:10.1007/BF00956170

upstream raw materials:

2,4,4,6-tetrachloro-hexanoic acid methyl ester

7-cyclopropylmercuric bromide

acrylic acid methyl ester

Downstream raw materials:

methyl 4-methylpentanoate

methyl hexanoate

cyclobutanecarboxylic acid {3-[5-cyclopropylmethyl-2-(3-fluoro-phenylamino)-pyrimidin-4-ylamino]-propyl}-amide