4-tert-ButylbenzhydroxaMic Acid

Base Information

Chemical Name:4-tert-ButylbenzhydroxaMic Acid
CAS No.:62034-73-5
Molecular Formula:C11H15NO2
Molecular Weight:193.246
Hs Code.:
Mol file:62034-73-5.mol

Synonyms:p-tert-butyl benzohydroxamic acid;

Suppliers and Price of 4-tert-ButylbenzhydroxaMic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-tert-ButylbenzhydroxamicAcid
500mg
$ 1260.00

Matrix Scientific
4-tert-Butyl-N-hydroxybenzamide 95%
25g
$ 3760.00

Matrix Scientific
4-tert-Butyl-N-hydroxybenzamide 95%
5g
$ 1175.00

Total 6 raw suppliers

Chemical Property of 4-tert-ButylbenzhydroxaMic Acid

Chemical Property:

PSA：49.33000
LogP:2.49400

Purity/Quality:

99%, ^*data from raw suppliers

4-tert-ButylbenzhydroxamicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 4-(tert-Butyl)benzhdroxamic Acid has shown signs of inhibition against histone deacetylases for application in the treatment of cancer. In addition this molecule displays antagonistic activity of PqsR (Pseudomonas aeruginose Transcriptional Regulator).

Technology Process of 4-tert-ButylbenzhydroxaMic Acid

There total 5 articles about 4-tert-ButylbenzhydroxaMic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 26537-19-9
methyl 4-tert-butylbenzoate

: 62034-73-5
p-tert-butyl benzohydroxamic acid

Guidance literature:: With hydroxylamine hydrochloride; potassium hydroxide; In methanol; at 20 ℃; for 12h; pH=10;
DOI:10.1039/c6ob01178k

Reference yield: 79.0%

: 877-65-6
p-tert-butylbenzyl alcohol

: 62034-73-5
p-tert-butyl benzohydroxamic acid

Guidance literature:: p-tert-butylbenzyl alcohol; With 1-hydroxy-pyrrolidine-2,5-dione; [bis(acetoxy)iodo]benzene; In acetonitrile; at 0 - 20 ℃; for 3h; Inert atmosphere; Green chemistry;

With hydroxylamine; In water; acetonitrile; for 12h; Inert atmosphere; Green chemistry;
DOI:10.1039/c4ob00693c

Reference yield: 50.0%

: 98-73-7
4-(1,1-dimethylethyl)benzoic acid

: 62034-73-5
p-tert-butyl benzohydroxamic acid

Guidance literature:: 4-(1,1-dimethylethyl)benzoic acid; With 4-(Methylamino)pyridine; diisopropyl-carbodiimide; In dichloromethane; at 20 ℃;

With hydroxylamine; In dichloromethane; water; at 20 ℃; Further stages.;
DOI:10.1016/j.tetlet.2007.12.073