N-(4-chlorophenyl)-4,5-dihydro-1,3-thiazol-2-amine

Base Information

Chemical Name:N-(4-chlorophenyl)-4,5-dihydro-1,3-thiazol-2-amine
CAS No.:56242-68-3
Molecular Formula:C9H9ClN2S
Molecular Weight:212.6992
Hs Code.:
NSC Number:201528
DSSTox Substance ID:DTXSID20308030
Nikkaji Number:J597.765G
Wikidata:Q82055684

Synonyms:N-(4-chlorophenyl)-4,5-dihydro-1,3-thiazol-2-amine;56242-68-3;NSC201528;Maybridge1_005806;DivK1c_002094;HMS557P20;DTXSID20308030;STL265342;AKOS008946847;CCG-249654;NSC-201528;CDS1_001054

Suppliers and Price of N-(4-chlorophenyl)-4,5-dihydro-1,3-thiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of N-(4-chlorophenyl)-4,5-dihydro-1,3-thiazol-2-amine

Chemical Property:

Vapor Pressure:0.000165mmHg at 25°C
Boiling Point:330.6°C at 760 mmHg
Flash Point:153.7°C
Density:1.38g/cm³
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:212.0174972
Heavy Atom Count:13
Complexity:200

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CSC(=N1)NC2=CC=C(C=C2)Cl

Technology Process of N-(4-chlorophenyl)-4,5-dihydro-1,3-thiazol-2-amine

There total 9 articles about N-(4-chlorophenyl)-4,5-dihydro-1,3-thiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 1848-62-0
1-(4-chloro-phenyl)-3-(2-hydroxy-ethyl)-thiourea

: 56242-68-3
p-chlorophenylamino-2 dihydro-4,5 thiazole

Guidance literature:: With hydrogenchloride; sodium carbonate; for 24h; Heating;
DOI:10.1016/0223-5234(89)90011-1

Reference yield: 29.0%

: 2131-55-7
4-Chlorophenyl isothiocyanate

: 20261-59-0,56633-27-3,85338-41-6
monoethanolammonium hydrogensulfate

: 56242-68-3
(4-Chloro-phenyl)-thiazolidin-(2Z)-ylidene-amine

Guidance literature:: With sodium hydroxide; In ethanol; for 3h; Heating;

Reference yield:

: 43009-19-4
p-chlorophenyldithiocarbamic acid triethylamine salt

: 56242-68-3
p-chlorophenylamino-2 dihydro-4,5 thiazole

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / CHCl₃ / 1 h / Ambient temperature

2: 3 N HCl, triethylamine / CHCl₃

3: acetone / 5 h / Heating

4: 51 percent / 1.) 6 N HCl; 2.) 10 percent Na₂CO₃, pH=10-11 / 24 h / Heating

With hydrogenchloride; sodium carbonate; triethylamine; In chloroform; acetone;
DOI:10.1016/0223-5234(89)90011-1