1H-Isoindole-1,3(2H)-dione, 2-[[(4-nitrobenzoyl)oxy]methyl]-

Base Information

Chemical Name:1H-Isoindole-1,3(2H)-dione, 2-[[(4-nitrobenzoyl)oxy]methyl]-
CAS No.:62153-82-6
Molecular Formula:C16H10N2O6
Molecular Weight:326.265
Hs Code.:
DSSTox Substance ID:DTXSID90358446
Wikidata:Q82139013
ChEMBL ID:CHEMBL366700

Synonyms:62153-82-6;1H-Isoindole-1,3(2H)-dione, 2-[[(4-nitrobenzoyl)oxy]methyl]-;CHEMBL366700;DTXSID90358446;AKOS003249403;SR-01000254574;SR-01000254574-1

Suppliers and Price of 1H-Isoindole-1,3(2H)-dione, 2-[[(4-nitrobenzoyl)oxy]methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1H-Isoindole-1,3(2H)-dione, 2-[[(4-nitrobenzoyl)oxy]methyl]-

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:326.05388604
Heavy Atom Count:24
Complexity:525

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C2=O)COC(=O)C3=CC=C(C=C3)[N+](=O)[O-]

Technology Process of 1H-Isoindole-1,3(2H)-dione, 2-[[(4-nitrobenzoyl)oxy]methyl]-

There total 5 articles about 1H-Isoindole-1,3(2H)-dione, 2-[[(4-nitrobenzoyl)oxy]methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 5332-26-3
N-(bromomethyl)phtalimide

: 62-23-7
4-nitro-benzoic acid

: 62153-82-6
(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl 4-nitrobenzoate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 2h;
DOI:10.1371/journal.pone.0119440

Reference yield:

: 496-11-7
INDANE

: 62153-82-6
(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl 4-nitrobenzoate

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid; potassium dichromate / 3 h / 120 °C

2.1: ammonium hydroxide / Reflux; Heating

3.1: potassium hydroxide / ethanol / 4 h / Reflux

3.2: 4 h / 70 °C

4.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C

With potassium dichromate; ammonium hydroxide; potassium carbonate; acetic acid; potassium hydroxide; In ethanol; N,N-dimethyl-formamide;
DOI:10.1371/journal.pone.0119440

Reference yield:

: 85-44-9
phthalic anhydride

: 62153-82-6
(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl 4-nitrobenzoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: ammonium hydroxide / Reflux; Heating

2.1: potassium hydroxide / ethanol / 4 h / Reflux

2.2: 4 h / 70 °C

3.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C

With ammonium hydroxide; potassium carbonate; potassium hydroxide; In ethanol; N,N-dimethyl-formamide;
DOI:10.1371/journal.pone.0119440