Benzenemethanol, 2-[[2-[(dimethylamino)methyl]phenyl]thio]-

Base Information

Chemical Name:Benzenemethanol, 2-[[2-[(dimethylamino)methyl]phenyl]thio]-
CAS No.:62220-57-9
Molecular Formula:C16H19NOS
Molecular Weight:273.399
Hs Code.:
DSSTox Substance ID:DTXSID80356597
Wikidata:Q82136039

Synonyms:62220-57-9;Benzenemethanol, 2-[[2-[(dimethylamino)methyl]phenyl]thio]-;SCHEMBL11632956;DTXSID80356597;AKOS005066509

Suppliers and Price of Benzenemethanol, 2-[[2-[(dimethylamino)methyl]phenyl]thio]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzenemethanol, 2-[[2-[(dimethylamino)methyl]phenyl]thio]-

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:273.11873540
Heavy Atom Count:19
Complexity:259

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)CC1=CC=CC=C1SC2=CC=CC=C2CO

Technology Process of Benzenemethanol, 2-[[2-[(dimethylamino)methyl]phenyl]thio]-

There total 9 articles about Benzenemethanol, 2-[[2-[(dimethylamino)methyl]phenyl]thio]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 62220-54-6
2-carbethoxy-2'-<(dimethylamino)carbonyl>diphenyl sulfide

: 62220-57-9
2-<(dimethylamino)methyl>-2'-(hydroxymethyl)diphenyl sulfide

Guidance literature:: In tetrahydrofuran;

Reference yield:

: 22219-02-9
2,2'-thiodibenzoic acid

: 62220-57-9
2-<(dimethylamino)methyl>-2'-(hydroxymethyl)diphenyl sulfide

Guidance literature:: Multi-step reaction with 6 steps

1: thionyl chloride / 5 h / 60 °C

2: 0.5 h / Heating

3: 37 percent / KOH / ethanol / 96 h / Ambient temperature

4: 20.1 g / thionyl chloride

5: 27.0 g / dioxane; H₂O / 1 h

6: LiAlH₄ / tetrahydrofuran / Ambient temperature

With potassium hydroxide; lithium aluminium tetrahydride; thionyl chloride; In tetrahydrofuran; 1,4-dioxane; ethanol; water;
DOI:10.1021/jo00321a020

Reference yield:

: 62220-52-4
2-carbethoxy-2'-carboxydiphenyl sulfide

: 62220-57-9
2-<(dimethylamino)methyl>-2'-(hydroxymethyl)diphenyl sulfide

Guidance literature:: Multi-step reaction with 3 steps

1: 20.1 g / thionyl chloride

2: 27.0 g / dioxane; H₂O / 1 h

3: LiAlH₄ / tetrahydrofuran / Ambient temperature

With lithium aluminium tetrahydride; thionyl chloride; In tetrahydrofuran; 1,4-dioxane; water;
DOI:10.1021/jo00321a020