Eclosion hormone

Base Information

• Chemical Name: Eclosion hormone
• CAS No.: 86836-08-0
• Molecular Formula: C9H13N2O8P
• Molecular Weight: 308.181881
• Mol file: 86836-08-0.mol

Synonyms:

Chemical Property of Eclosion hormone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Description: The eclosion hormone is a brain neuropeptide that controls the release of the ecdysis-triggering hormone (ETH) from Inka cells and activates a network of 27/704 neurons in the ventral nerve cord responsible for ecdysis behavior and postecdysis processes in moths, flies, and probably other insects.
• Biological functions: There are central and peripheral roles of EH in moths. Centrally released EH activates a network of neurons (27/704) through the elevation of cGMP that is specific for the regulation of ecdysis and postecdysis processes. Peripherally released EH elicits cGMP production in endocrine Inka cells and causes massive ETH secretion to activate additional neurons controlling ecdysis.EH probably controls tracheal inflation and may act on Verson’s glands during ecdysis.Together with VM cells, EH-expressing D1 and Dm neurons govern adult ecdysis behavior in Drosophila. Persistance of D1 cells into adulthood suggests their different, albeit unknown, function. Presumptive release sites of D1 cells in medula suggest that they may modulate visual processing and possibly also“gate” adult eclosion after light exposure in flies. Function of somatically expressed EH remains to be examined but it may relate to the air-filling of the new tracheae.