1-(1-trityl-1H-imidazol-4-yl)propan-1-ol

Base Information

Chemical Name:1-(1-trityl-1H-imidazol-4-yl)propan-1-ol
CAS No.:62256-51-3
Molecular Formula:C25H24N2O
Molecular Weight:368.478
Hs Code.:
DSSTox Substance ID:DTXSID701225503

Synonyms:1-(1-trityl-1H-imidazol-4-yl)propan-1-ol;62256-51-3;SCHEMBL5060964;YWLLPHMRKPVQBT-UHFFFAOYSA-N;DTXSID701225503;FT-0740139;alpha-Ethyl-1-(triphenylmethyl)-1H-imidazole-4-methanol

Suppliers and Price of 1-(1-trityl-1H-imidazol-4-yl)propan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(1-trityl-1H-imidazol-4-yl)propan-1-ol

Chemical Property:

XLogP3:4.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:368.188863393
Heavy Atom Count:28
Complexity:418

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C1=CN(C=N1)C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)O

Technology Process of 1-(1-trityl-1H-imidazol-4-yl)propan-1-ol

There total 3 articles about 1-(1-trityl-1H-imidazol-4-yl)propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 33016-47-6
(1-tritylimidazol-4-yl)carboxaldehyde

: 62256-51-3
1-(1-trityl-1H-imidazol-4-yl)propan-1-ol

Guidance literature:: ethyl iodide; With tert.-butyl lithium; In diethyl ether; pentane; at -70 - 20 ℃; for 1.05h;

(1-tritylimidazol-4-yl)carboxaldehyde; In tetrahydrofuran; diethyl ether; pentane; at 0 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; diethyl ether; water; pentane; pH=3 - 5;

Reference yield:

: 925-90-6
ethylmagnesium bromide

: 33016-47-6
(1-tritylimidazol-4-yl)carboxaldehyde

: 62256-51-3
1-(1-trityl-1H-imidazol-4-yl)propan-1-ol

Guidance literature:: In tetrahydrofuran; at 20 ℃; for 24h;
DOI:10.1055/s-2007-983758

Reference yield:

: 76-83-5
trityl chloride

: 62256-51-3
1-(1-trityl-1H-imidazol-4-yl)propan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / N,N-dimethyl-formamide / 0 - 35 °C

2: tetrahydrofuran / 18 h / 0 - 35 °C

With triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide;