BETA-OXO-BENZENEPENTANOIC ACID PHENYLMETHYL ESTER

Base Information

• Chemical Name: BETA-OXO-BENZENEPENTANOIC ACID PHENYLMETHYL ESTER
• CAS No.: 62282-45-5
• Molecular Formula: C18H18O3
• Molecular Weight: 282.339
• Mol file: 62282-45-5.mol

Synonyms:3-Oxo-5-phenyl-pentanoic acid benzyl ester;Benzyl-γ-benzylacetoacetat;

Chemical Property of BETA-OXO-BENZENEPENTANOIC ACID PHENYLMETHYL ESTER

Chemical Property:

• Boiling Point: 160 - 163 °C (0.1 mmHg)
• PSA: 43.37000
• LogP: 3.32180

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BETA-OXO-BENZENEPENTANOIC ACID PHENYLMETHYL ESTER

There total 5 articles about BETA-OXO-BENZENEPENTANOIC ACID PHENYLMETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

(+/-)-benzyl 5-phenyl-penta-2,3-dienoate (1206636-18-1) → benzyl 3-oxo-5-phenylpentanoate (62282-45-5)

Guidance literature:

With Oxone; In water; N,N-dimethyl-formamide; at 80 ℃; Green chemistry;

DOI:10.1016/j.tetlet.2015.05.120

Reference yield:

ethyl 3-oxo-5-phenylpentanoate (17071-29-3) → benzyl 3-oxo-5-phenylpentanoate (62282-45-5)

Guidance literature:

With benzyl alcohol;

Reference yield:

ethyl 3-oxo-5-phenylpentanoate (17071-29-3) + benzyl alcohol (100-51-6,185532-71-2) → benzyl 3-oxo-5-phenylpentanoate (62282-45-5)

Guidance literature:

at 170 ℃;

DOI:10.1139/v77-070

upstream raw materials:

ethyl 3-oxo-5-phenylpentanoate

benzyl alcohol

phenethylmagnesium bromide

(+/-)-benzyl 5-phenyl-penta-2,3-dienoate

Downstream raw materials:

2-[(E)-Hydroxyimino]-3-oxo-5-phenyl-pentanoic acid benzyl ester

3-(ethoxycarbonyl)-4-(2-phenylethyl)-5-<(phenylmethoxy)carbonyl>-1H-pyrrole-2-acetic acid, ethyl ester

5-Chlorocarbonyl-2-ethoxycarbonylmethyl-1-methyl-4-phenethyl-1H-pyrrole-3-carboxylic acid ethyl ester

5-carboxy-3-(ethoxycarbonyl)-1-methyl-4-(2-phenylethyl)-1H-pyrrole-2-acetic acid, ethyl ester