6H-Pyrido(4,3-b)carbazol-9-ol, 1-((3-(diethylamino)propyl)amino)-5,11-dimethyl-

Base Information

• Chemical Name: 6H-Pyrido(4,3-b)carbazol-9-ol, 1-((3-(diethylamino)propyl)amino)-5,11-dimethyl-
• CAS No.: 72238-05-2
• Molecular Formula: C₂₄H₃₀N₄O
• Molecular Weight: 390.528
• DSSTox Substance ID: DTXSID40222562
• Nikkaji Number: J66.636J
• Wikidata: Q83100833
• ChEMBL ID: CHEMBL282444
• Mol file: 72238-05-2.mol

Synonyms:72238-05-2;6H-Pyrido(4,3-b)carbazol-9-ol, 1-((3-(diethylamino)propyl)amino)-5,11-dimethyl-;CHEMBL282444;BRN 0717969;1-((3-(Diethylamino)propyl)amino)-5,11-dimethyl-6H-pyrido(4,3-b)carbazol-9-ol;1-((3-(Diethylamino)propyl)amino)-5,11-dimethyl-9-hydroxy-6H-pyrido(4,3-b)carbazole;SCHEMBL2314298;DTXSID40222562;BDBM50174410;1-(3-Diethylamino-propylamino)-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-9-ol

Chemical Property of 6H-Pyrido(4,3-b)carbazol-9-ol, 1-((3-(diethylamino)propyl)amino)-5,11-dimethyl-

Chemical Property:

• Vapor Pressure: 3.17E-17mmHg at 25°C
• Boiling Point: 644.8°C at 760 mmHg
• Flash Point: 343.8°C
• Density: 1.22g/cm³
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 390.24196159
• Heavy Atom Count: 29
• Complexity: 527

Purity/Quality:

99% ^*data from raw suppliers

1-((3-(DIETHYLAMINO)PROPYL)AMINO)-5,11-DIMETHYL-6H-PYRIDO-(4,3-B)CARBAZ OL-9-OL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)CCCNC1=NC=CC2=C(C3=C(C(=C21)C)C4=C(N3)C=CC(=C4)O)C

Technology Process of 6H-Pyrido(4,3-b)carbazol-9-ol, 1-((3-(diethylamino)propyl)amino)-5,11-dimethyl-

There total 5 articles about 6H-Pyrido(4,3-b)carbazol-9-ol, 1-((3-(diethylamino)propyl)amino)-5,11-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9-hydroxy-5,11-dimethoxy-6H-pyrido<4,3-b>carbazol-1(2H)-one (83947-93-7) → 1-<<3-(diethylamino)propyl>amino>-9-hydroxy-5,11-dimethyl-6H-pyrido<4,3-b>carbazole (72238-05-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 65 percent / pyridine / 1 h / Heating

2: 72 percent / phosphorus oxychloride / 3 h / Heating

3: 2 h / 160 °C

With pyridine; trichlorophosphate;

DOI:10.1021/jm00356a012

Reference yield:

9-(benzoyloxy)-5,11-dimethyl-6H-pyrido<4,3-b>carbazol-1(2H)-one (83947-94-8) → 1-<<3-(diethylamino)propyl>amino>-9-hydroxy-5,11-dimethyl-6H-pyrido<4,3-b>carbazole (72238-05-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / phosphorus oxychloride / 3 h / Heating

2: 2 h / 160 °C

With trichlorophosphate;

DOI:10.1021/jm00356a012

Reference yield:

1,2-Dihydro-5,11-dimethyl-9-methoxy-1-oxo-6H-pyrido<4,3-b>carbazole (72237-94-6) → 1-<<3-(diethylamino)propyl>amino>-9-hydroxy-5,11-dimethyl-6H-pyrido<4,3-b>carbazole (72238-05-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 54 percent / pyridine hydrochloride / 0.5 h / 220 - 230 °C / Heating

2: 65 percent / pyridine / 1 h / Heating

3: 72 percent / phosphorus oxychloride / 3 h / Heating

4: 2 h / 160 °C

With pyridine; pyridine hydrochloride; trichlorophosphate;

DOI:10.1021/jm00356a012

upstream raw materials:

1-chloro-9-(benzoyloxy)-5,11-dimethyl-6H-pyrido<4,3-b>carbazole

diethylaminopropylamine

9-hydroxy-5,11-dimethoxy-6H-pyrido<4,3-b>carbazol-1(2H)-one

9-(benzoyloxy)-5,11-dimethyl-6H-pyrido<4,3-b>carbazol-1(2H)-one