Phosphinic acid, (1-hydroxycyclohexyl)phenyl-, ethyl ester

Base Information

Chemical Name:Phosphinic acid, (1-hydroxycyclohexyl)phenyl-, ethyl ester
CAS No.:62299-66-5
Molecular Formula:C14H21O3P
Molecular Weight:268.293
Hs Code.:
DSSTox Substance ID:DTXSID30353713
ChEMBL ID:CHEMBL1734026

Synonyms:1-[ethoxy(phenyl)phosphoryl]cyclohexan-1-ol;Phosphinic acid, (1-hydroxycyclohexyl)phenyl-, ethyl ester;62299-66-5;SMR000141512;Oprea1_622663;MLS000534074;CHEMBL1734026;DTXSID30353713;HMS1587M01;HMS2305H17;ethyl (1-hydroxycyclohexyl)phenylphosphinate;EU-0079248;AB00113934-01;SR-01000499557;SR-01000499557-1

Suppliers and Price of Phosphinic acid, (1-hydroxycyclohexyl)phenyl-, ethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Phosphinic acid, (1-hydroxycyclohexyl)phenyl-, ethyl ester

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:268.12283153
Heavy Atom Count:18
Complexity:304

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOP(=O)(C1=CC=CC=C1)C2(CCCCC2)O

Technology Process of Phosphinic acid, (1-hydroxycyclohexyl)phenyl-, ethyl ester

There total 2 articles about Phosphinic acid, (1-hydroxycyclohexyl)phenyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 172487-18-2,2511-09-3
ethyl Phenylphosphinate

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 62299-66-5
ethyl (1-hydroxy-1-cyclohexyl)phenylphosphinate

Guidance literature:: for 72h; Inert atmosphere; Schlenk technique; Reflux;
DOI:10.1002/ejoc.201801518

Reference yield:

: 62299-66-5
ethyl (1-hydroxy-1-cyclohexyl)phenylphosphinate

Guidance literature:: Phosphinylchlorid I, Ethanol;
DOI:10.1007/BF00973428

Reference yield: 71.0%

: 14044-65-6
borane-THF

: 62299-66-5
ethyl (1-hydroxy-1-cyclohexyl)phenylphosphinate

: (1-hydroxy-1-cyclohexyl)phenylphosphinous acid borane ethyl ester

: (1-hydroxy-1-cyclohexyl)phenylphosphine borane

Guidance literature:: In tetrahydrofuran; at 60 ℃; for 24h; chemoselective reaction; Inert atmosphere; Schlenk technique;
DOI:10.1002/ejoc.201801518