3-Isoxazolecarboxylic acid hydrazide

Base Information

• Chemical Name: 3-Isoxazolecarboxylic acid hydrazide
• CAS No.: 62438-02-2
• Molecular Formula: C4H5N3O2
• Molecular Weight: 127.10100
• Mol file: 62438-02-2.mol

Synonyms:3-isoxazolecarbohydrazide;Isoxazol-3-carbonsaeure-hydrazid;isoxazole-3-carboxylic acid hydrazide;ISOXAZOLE-3-CARBOHYDRAZIDE;3-Isoxazolecarboxylic acid,hydrazide;4-ISOXAZOLE-CARBOXYHYDRAZIDE;

Chemical Property of 3-Isoxazolecarboxylic acid hydrazide

Chemical Property:

• PSA: 81.15000
• LogP: 0.36930

Purity/Quality:

99% ，98% ^*data from raw suppliers

isoxazole-3-carbohydrazide 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Isoxazolecarboxylic acid hydrazide

There total 3 articles about 3-Isoxazolecarboxylic acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ isoxazole-3-carbohydrazide (62438-02-2)

Guidance literature:

Reference yield:

1,1-dimethylethyl 2-(3-isoxazolylcarbonyl)hydrazinecarboxylate (1254073-72-7) → isoxazole-3-carbohydrazide (62438-02-2)

Guidance literature:

1,1-dimethylethyl 2-(3-isoxazolylcarbonyl)hydrazinecarboxylate; With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 6h; Inert atmosphere;

With ammonia; In methanol;

Reference yield:

isoxazole-3-carboxamide (29065-91-6) → isoxazole-3-carbohydrazide (62438-02-2)

Guidance literature:

With hydrazine hydrate;

upstream raw materials:

isoxazole-3-carboxamide

1,1-dimethylethyl 2-(3-isoxazolylcarbonyl)hydrazinecarboxylate

Refernces

• 1、 -. "5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-a]PYRAZINE DERIVATIVES AS P2X7 MODULATORS". Page/Page column 106. . Retrieved 2010/11/17.