Taccalonolide B

Base Information

• Chemical Name: Taccalonolide B
• CAS No.: 108885-69-4
• Molecular Formula: C₃₄H₄₄O₁₃
• Molecular Weight: 660.716
• Mol file: 108885-69-4.mol

Synonyms:2H-Oxireno[6',7']naphtho[1',2':7,8]fluoreno[2,1-b]furan,16,24-cycloergost-22-en-26-oic acid deriv.; Taccalonolide B

Chemical Property of Taccalonolide B

Chemical Property:

• PSA: 195.49000
• Density: 1.43±0.1 g/cm3 (20 oC 760 Torr)
• LogP: 0.84180

Purity/Quality:

≥98% ^*data from raw suppliers

taccalonolide B ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Taccalonolide B

There total 2 articles about Taccalonolide B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

taccalonolide A (108885-68-3) → taccalonolide B (108885-69-4)

Guidance literature:

With water; sodium hydrogencarbonate; In methanol;

DOI:10.1021/acs.jnatprod.7b00967

Reference yield: 80.0%

taccalonolide A (108885-68-3) → taccalonolide AO + taccalonolide B (108885-69-4) + taccalonolide I

Guidance literature:

With water; sodium hydrogencarbonate; In methanol; at 20 ℃; for 20h;

DOI:10.1021/np400435t

Reference yield:

taccalonolide B (108885-69-4) → C49H62N2O16S

Guidance literature:

Multi-step reaction with 3 steps

1: methanol; ammonium acetate; sodium cyanoborohydride / 16 h / 20 °C / Molecular sieve

2: 3,3-dimethyldioxirane / acetone / 4 h / -20 °C

3: pH 7

With methanol; ammonium acetate; 3,3-dimethyldioxirane; sodium cyanoborohydride; In acetone;

upstream raw materials:

taccalonolide A

Downstream raw materials:

taccalonolide AJ

taccalonolide A