3,5-Pyrazolidinedione, 4-(4-hydroxy-3-methyl-2-butenyl)-1-(4-hydroxyphenyl)-2-phenyl-

Base Information

Chemical Name:3,5-Pyrazolidinedione, 4-(4-hydroxy-3-methyl-2-butenyl)-1-(4-hydroxyphenyl)-2-phenyl-
CAS No.:77165-72-1
Molecular Formula:C₂₀H₂₀N₂O₄
Molecular Weight:352.39
Hs Code.:

Synonyms:3,5-Pyrazolidinedione, 4-(4-hydroxy-3-methyl-2-butenyl)-1-(4-hydroxyphenyl)-2-phenyl-;77165-72-1

Suppliers and Price of 3,5-Pyrazolidinedione, 4-(4-hydroxy-3-methyl-2-butenyl)-1-(4-hydroxyphenyl)-2-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3,5-Pyrazolidinedione, 4-(4-hydroxy-3-methyl-2-butenyl)-1-(4-hydroxyphenyl)-2-phenyl-

Chemical Property:

Vapor Pressure:6.11E-13mmHg at 25°C
Boiling Point:550.2°Cat760mmHg
Flash Point:286.6°C
Density:1.311g/cm³
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:352.14230712
Heavy Atom Count:26
Complexity:548

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=CCC1C(=O)N(N(C1=O)C2=CC=C(C=C2)O)C3=CC=CC=C3)CO
Isomeric SMILES:C/C(=C\CC1C(=O)N(N(C1=O)C2=CC=C(C=C2)O)C3=CC=CC=C3)/CO

Technology Process of 3,5-Pyrazolidinedione, 4-(4-hydroxy-3-methyl-2-butenyl)-1-(4-hydroxyphenyl)-2-phenyl-

There total 20 articles about 3,5-Pyrazolidinedione, 4-(4-hydroxy-3-methyl-2-butenyl)-1-(4-hydroxyphenyl)-2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: (E)-4-(3-hydroxymethyl-but-2-enyl)-1-(4-(β-methoxyethoxymethoxy)-phenyl)-2-phenyl-3,5-pyrazolidinedione

: 77165-72-1
(E)-4-(3-hydroxymethyl-but-2-enyl)-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidinedione

Guidance literature:: With zinc dibromide; In dichloromethane; Ambient temperature;

Reference yield:

: 4-(p-methoxyethoxymethoxy)-azobenzene

: 77165-72-1
(Z)-4-(3-hydroxymethyl-but-2-enyl)-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidinedione

Guidance literature:: Multi-step reaction with 6 steps

1: 99 percent / hydrogen / Pd/C / ethanol / Ambient temperature

2: 50 percent / NaOEt / ethanol / reflux, 3 h; 130 to 140 deg C under reduced pressure (15 Torr)

3: 56 percent / H₂O / ethanol / 64 h / Heating

4: 3 percent / dimethylsulfoxide / RT, 1 h; 60 deg C, 1 h; RT, 16 h

5: Red-Al (70percent in toluene) / benzene / 3 h / Ambient temperature

6: ZnBr₂ / CH₂Cl₂ / Ambient temperature

With water; hydrogen; sodium ethanolate; sodium bis(2-methoxyethoxy)aluminium dihydride; zinc dibromide; palladium on activated charcoal; In ethanol; dichloromethane; dimethyl sulfoxide; benzene;

Reference yield:

: 4-(p-methoxyethoxymethoxy)-azobenzene

: 77165-72-1
(E)-4-(3-hydroxymethyl-but-2-enyl)-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidinedione

Guidance literature:: Multi-step reaction with 5 steps

1: 99 percent / hydrogen / Pd/C / ethanol / Ambient temperature

2: 38 percent / n-BuONa / butan-1-ol / reflux, 30 min; 160 deg C, 1 h under 15 Torr

3: 36 percent / dimethylformamide; H₂O / 0 deg C, 1 h, RT, 16 h

4: 5percent NaOH / 3 h / Ambient temperature

5: 32 percent / ZnBr₂ / CH₂Cl₂ / Ambient temperature

With sodium hydroxide; hydrogen; sodium butanolate; zinc dibromide; palladium on activated charcoal; In ethanol; dichloromethane; water; N,N-dimethyl-formamide; butan-1-ol;