2H-1-Benzopyran-6-carboxylic acid, 5-methoxy-2,2-dimethyl-

Base Information

Chemical Name:2H-1-Benzopyran-6-carboxylic acid, 5-methoxy-2,2-dimethyl-
CAS No.:62499-04-1
Molecular Formula:C13H14O4
Molecular Weight:234.252
Hs Code.:

Synonyms:2H-1-Benzopyran-6-carboxylic acid,5-methoxy-2,2-dimethyl;5-Methoxy-2,2-dimethyl-2H-chromen-6-carbonsaeure;5-methoxy-2,2-dimethyl-2H-chromene-6-carboxylic acid;

Suppliers and Price of 2H-1-Benzopyran-6-carboxylic acid, 5-methoxy-2,2-dimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
5-Methoxy-2,2-dimethyl-2H-1-benzopyran-6-carboxylicacid
250mg
$ 667.00

Total 2 raw suppliers

Chemical Property of 2H-1-Benzopyran-6-carboxylic acid, 5-methoxy-2,2-dimethyl-

Chemical Property:

Boiling Point:386.0±42.0 °C(Predicted)
PSA：55.76000
Density:1?+-.0.06 g/cm3(Predicted)
LogP:2.57760

Purity/Quality:

99% ^*data from raw suppliers

5-Methoxy-2,2-dimethyl-2H-1-benzopyran-6-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2H-1-Benzopyran-6-carboxylic acid, 5-methoxy-2,2-dimethyl-

There total 7 articles about 2H-1-Benzopyran-6-carboxylic acid, 5-methoxy-2,2-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 79571-17-8
5-(methoxy)-2,2-dimethyl-2H-chromene-6-carbaldehyde

: 62499-04-1
5-methoxy-2,2-dimethyl-2H-chromene-6-carboxylic acid

Guidance literature:: With sodium chlorite; dihydrogen peroxide; In acetonitrile; at 0 - 20 ℃; for 5h;
DOI:10.1016/j.bmc.2019.02.040

Reference yield:

: 95-01-2
2,4-Dihydroxybenzaldehyde

: 62499-04-1
5-methoxy-2,2-dimethyl-2H-chromene-6-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine; calcium(II) chloride dihydrate / ethanol / 1 h / Reflux; Inert atmosphere

2: potassium carbonate / acetone / 12 h / Reflux; Inert atmosphere

3: sodium hydroxide; silver nitrate / water / Reflux; Inert atmosphere

With calcium(II) chloride dihydrate; potassium carbonate; silver nitrate; triethylamine; sodium hydroxide; In ethanol; water; acetone;
DOI:10.1021/acs.jmedchem.8b00971

Reference yield:

: 54287-99-9
5-hydroxy-2,2-dimethyl-2H-chromene-6-carbaldehyde

: 62499-04-1
5-methoxy-2,2-dimethyl-2H-chromene-6-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 12 h / Reflux; Inert atmosphere

2: sodium hydroxide; silver nitrate / water / Reflux; Inert atmosphere

With potassium carbonate; silver nitrate; sodium hydroxide; In water; acetone;
DOI:10.1021/acs.jmedchem.8b00971