3-ETHYL-5-[(PHENYLAMINO)METHYLENE]-2-THIOXO-4-THIAZOLIDINONE

Base Information

• Chemical Name: 3-ETHYL-5-[(PHENYLAMINO)METHYLENE]-2-THIOXO-4-THIAZOLIDINONE
• CAS No.: 39542-83-1
• Molecular Formula: C12H12 N2 O S2
• Molecular Weight: 264.372
• Hs Code.: 2934999090
• Mol file: 39542-83-1.mol

Synonyms:Rhodanine,5-(anilinomethylene)-3-ethyl- (6CI,7CI); 3-Ethyl-5-anilidomethylenerhodanine;5-(Anilinomethylene)-3-ethyl-2-thioxo-4-thiazolidinone

Chemical Property of 3-ETHYL-5-[(PHENYLAMINO)METHYLENE]-2-THIOXO-4-THIAZOLIDINONE

Chemical Property:

• Vapor Pressure: 1.51E-05mmHg at 25°C
• Boiling Point: 366 ºC at 760 mmHg
• Flash Point: 175.1ºC
• PSA: 89.73000
• Density: 1.36 g/cm³
• LogP: 2.83100

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-ETHYL-5-[(PHENYLAMINO)METHYLENE]-2-THIOXO-4-THIAZOLIDINONE

There total 5 articles about 3-ETHYL-5-[(PHENYLAMINO)METHYLENE]-2-THIOXO-4-THIAZOLIDINONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-ethylrhodanin (7648-01-3) + Ethyl N-phenylformimidate (6780-49-0) → 3-ethyl-5-((phenylamino)methylene)-2-thioxothiazolidin-4-one (39542-83-1)

Guidance literature:

In ethanol; for 0.416667h; Heating;

Reference yield: 73.0%

3-ethylrhodanin (7648-01-3) + N,N-diphenylformamidine (4538-56-1) → 3-ethyl-5-((phenylamino)methylene)-2-thioxothiazolidin-4-one (39542-83-1)

Guidance literature:

In acetonitrile; at 70 ℃; for 1h;

DOI:10.1016/j.bmc.2019.115187

Reference yield:

3-ethylrhodanin (7648-01-3) + N,N'-diphenylformamidine (864131-95-3) → 3-ethyl-5-((phenylamino)methylene)-2-thioxothiazolidin-4-one (39542-83-1)

Guidance literature:

With Petroleum ether; at 120 ℃;

DOI:10.1021/ja01155a095

upstream raw materials:

3-ethylrhodanin

N,N'-diphenylformamidine

5-ethoxymethylene-3-ethyl-2-thioxo-thiazolidin-4-one

aniline

Downstream raw materials:

N-(3-ethyl-4-oxo-2-thioxothiazolidin-5-ylidenemethyl)-N-phenylacetamide

5-anilinomethylene-3-ethyl-thiazolidine-2,4-dithione

C₁₃H₁₅N₂OS₂⁽¹⁺⁾*CH₃O₄S^(1-)

3-ethyl-5-[2-(1-phenyl-1H-quinolin-4-ylidene)-ethylidene]-thiazolidine-2,4-dithione